4-triphenylphosphoranylidenamino-benzoic acid | 31641-62-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-triphenylphosphoranylidenamino-benzoic acid
• 英文别名: 4-Triphenylphosphoranylidenamino-benzoesaeure；4-[(Triphenyl-lambda5-phosphanylidene)amino]benzoic acid；4-[(triphenyl-λ5-phosphanylidene)amino]benzoic acid
• CAS: 31641-62-0
• 化学式: C₂₅H₂₀NO₂P
• 分子量: 397.413
• InChiKey: BNJGYPYEHJPQJH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  29
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  49.7
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  对叠氮苯甲酸 、 三苯基膦 生成 4-triphenylphosphoranylidenamino-benzoic acid
  参考文献：
  名称：

  Kukhar',V.P. et al., Journal of general chemistry of the USSR, 1970, vol. 40, p. 1682 - 1685

  摘要：

  DOI：

文献信息

• Kukhar',V.P. et al., Journal of general chemistry of the USSR, 1970, vol. 40, p. 1682 - 1685
  作者：Kukhar',V.P. et al.

  DOI：——

  日期：——
• Kuchar et al., Zhurnal Obshchei Khimii, 1970, vol. 40, p. 1696,1698; engl.Ausg.S.1682,1684
  作者：Kuchar et al.

  DOI：——

  日期：——
• Light, Medium, and Heavy Fluorous Triarylphosphines Exhibit Comparable Reactivities to Triphenylphosphine in Typical Reactions of Triarylphosphines
  作者：Dennis P. Curran、Xiao Wang、Qisheng Zhang

  DOI：10.1021/jo050116j

  日期：2005.4.1

  The relative reactivities of triphenylphosphine (PPh3) and three fluorous triarylphosphines [(p-R-F(CH2)(2)C6H4)(n)PPh3-n, where n = 1-3] have been compared in internal competition experiments. Product ratios were determined by P-31 NMR spectroscopy. The four phosphines have about the same reactivities in oxidation, alkylation, and Staudinger reactions and give comparable yields in a preparative Mitsunobu reaction. Previously observed rate and yield differences in Staudinger reactions of the fluorous phosphines are attributed to solubility effects, not reactivity differences. A light fluorous phosphine [(p-C8F17(CH2)(2)C6H4)PPh2] outperforms a commercially available resin-bound phosphine in a competitive benzylation experiment by a factor of about 4.