1-(3-Nitro-phenyl)-2,3-dihydro-phosphole 1-oxide | 195317-22-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(3-Nitro-phenyl)-2,3-dihydro-phosphole 1-oxide
• 英文别名: 1H-Phosphole, 2,3-dihydro-1-(3-nitrophenyl)-, 1-oxide；1-(3-nitrophenyl)-2,3-dihydro-1λ5-phosphole 1-oxide
• CAS: 195317-22-7
• 化学式: C₁₀H₁₀NO₃P
• 分子量: 223.168
• InChiKey: PKEFSZPWSLJMNF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  62.9
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1-(3-Nitro-phenyl)-2,3-dihydro-phosphole 1-oxide 在 sodium peroxide 作用下， 以 乙醇 为溶剂， 反应 6.0h， 以80%的产率得到(1R,2S,5S)-2-(3-Nitro-phenyl)-6-oxa-2-phospha-bicyclo[3.1.0]hexane 2-oxide
  参考文献：
  名称：

  An efficient approach towards the stereospecific synthesis of epoxides from phospholene oxides

  摘要：

  A novel method has been developed for stereospecific conversion of 2-phospholene 1-oxides into their corresponding 2,3-epoxides in high yields using sodium peroxide as a reagent. (C) 2003 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(03)00255-7

文献信息

• An efficient approach towards the stereospecific synthesis of epoxides from phospholene oxides
  作者：Mitsuji Yamashita、Valluru Krishna Reddy、Lakonda Nagaprasada Rao、Buchammagari Haritha、Motoki Maeda、Keiji Suzuki、Hirono Totsuka、Masaki Takahashi、Tatsuo Oshikawa

  DOI：10.1016/s0040-4039(03)00255-7

  日期：2003.3

  A novel method has been developed for stereospecific conversion of 2-phospholene 1-oxides into their corresponding 2,3-epoxides in high yields using sodium peroxide as a reagent. (C) 2003 Elsevier Science Ltd. All rights reserved.