Butanamide, 4-[[(phenylamino)carbonyl](6-phenylhexyl)amino]- | 850882-99-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Butanamide, 4-[[(phenylamino)carbonyl](6-phenylhexyl)amino]-
• 英文别名: 4-[phenylcarbamoyl(6-phenylhexyl)amino]butanamide
• CAS: 850882-99-4
• 化学式: C₂₃H₃₁N₃O₂
• 分子量: 381.5
• InChiKey: XZNVGGUEWAQZAP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  28
• 可旋转键数：
  12
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.39
• 拓扑面积：
  75.4
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• AMIDE OR THIOAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PAIN
  申请人：CHANG Chia-Ping

  公开号：US20100105777A1

  公开（公告）日：2010-04-29

  The present invention relates to novel compounds, pharmaceutical compositions comprising the same, use of said compounds for the manufacture of a medicament for treatment of pain and disorders related thereto as well as a method for treatment of pain and disorders related thereto, wherein said compounds are administered. The compounds are represented by the general formula (I), as further defined in the specification.

  本发明涉及新型化合物、包含该化合物的药物组合物，以及使用该化合物制造治疗疼痛和相关疾病的药物以及治疗疼痛和相关疾病的方法，其中该化合物被给予。该化合物由一般式(I)表示，具体定义详见说明书。
• USE OF NOVEL COMPOUNDS FOR IBD TREATMENT
  申请人：Ferring BV

  公开号：EP1874283A2

  公开（公告）日：2008-01-09
• Amide or thioamide derivatives and their use in the treatment of pain
  申请人：Chang Chia-Ping

  公开号：US20070197653A1

  公开（公告）日：2007-08-23

  The present invention relates to novel compounds, pharmaceutical compositions comprising the same, use of said compounds for the manufacture of a medicament for treatment of pain and disorders related thereto as well as a method for treatment of pain and disorders related thereto, wherein said compounds are administered. The compounds are represented by the general formula (I), as further defined in the specification.
• Use of Novel Compounds for IBD Treatment
  申请人：Rivière Pierre J-M

  公开号：US20100261796A1

  公开（公告）日：2010-10-14

  The present invention relates to use of novel compounds for the manufacture of a medicament for treatment of inflammatory bowel disease (IBD) as well as to a method for treatment of IBD, wherein said compounds are administered. The compounds are represented by the general formula (I), as further defined in the specification.
• US7504538B2
  申请人：——

  公开号：US7504538B2

  公开（公告）日：2009-03-17