1,3,4-Nonadecanetriol, 2-amino-, (2S,3S,4R)- | 52795-55-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1,3,4-Nonadecanetriol, 2-amino-, (2S,3S,4R)-
• 英文别名: (2S,3S,4R)-2-aminononadecane-1,3,4-triol
• CAS: 52795-55-8
• 化学式: C₁₉H₄₁NO₃
• 分子量: 331.5
• InChiKey: PEOMDOQZOYXEHH-OTWHNJEPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  23
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  86.7
• 氢给体数：
  4
• 氢受体数：
  4

文献信息

• Method for producing acetylated sphingoid base
  申请人：Kao Corporation

  公开号：US10066249B2

  公开（公告）日：2018-09-04

  Provided is a means for producing an acetylated sphingoid base using modified microorganism in the genus Starmerella, particularly Starmerella bombicola. A method for producing an acetylated sphingoid base comprising culturing a microorganism in the genus Starmerella to which a xenogeneic gene encoding a polypeptide having an activity to acetylate a sphingoid base is introduced.

  本发明提供了一种利用改良星菌属微生物，特别是星菌 bombicola 生产乙酰化鞘氨醇碱的方法。生产乙酰化类鞘磷脂碱的方法包括培养星菌属微生物，在该微生物中引入编码具有乙酰化类鞘磷脂碱活性的多肽的异源基因。
• METHOD FOR PRODUCING ACETYLATED SPHINGOID BASE
  申请人：Kao Corporation

  公开号：EP3071700B1

  公开（公告）日：2022-07-20
• Method of Modulating Protein 14-3-3 Functionality By Facilitating or Inhibiting Phosphorylation
  申请人：Woodcock Joanna

  公开号：US20130231305A1

  公开（公告）日：2013-09-05

  The present invention relates to a method of modulating cellular activity. More particularly, the present invention provides a method of modulating apoptosis by modulating protein 14-3-3 phosphorylation and, thereby its functionality. The present invention still further extends to methods for identifying agents capable of modulating protein 14-3-3 phosphorylation. The method and molecules of the present invention are useful, inter alia, in the treatment and/or prophylaxis of conditions characterized by unwanted cellular activity, such as unwanted cell survival.
• Method for Producing Acetylated Sphingoid Base
  申请人：KAO CORPORATION

  公开号：US20160298150A1

  公开（公告）日：2016-10-13

  Provided is a means for producing an acetylated sphingoid base using modified microorganism in the genus Starmerella, particularly Starmerella bombicola. A method for producing an acetylated sphingoid base comprising culturing a microorganism in the genus Starmerella to which a xenogeneic gene encoding a polypeptide having an activity to acetylate a sphingoid base is introduced.
• [EN] A METHOD OF MODULATING PROTEIN 14-3-3 FUNCTIONALITY BY FACILITATING OR INHIBITING PHOSPHORYLATION<br/>[FR] PROCÉDÉ DE MODULATION DE LA FONCTIONNALITÉ DE LA PROTÉINE 14-3-3 PAR ACTIVATION OU INHIBITION DE LA PHOSPHORYLATION
  申请人：MEDVET SCIENCE PTY LTD

  公开号：WO2011120082A1

  公开（公告）日：2011-10-06

  The present invention relates to a method of modulating cellular activity. More particularly, the present invention provides a method of modulating apoptosis by modulating protein 14-3-3 phosphorylation and, thereby, its functionality. The present invention still further extends to methods for identifying agents capable of modulating protein 14-3-3 phosphorylation. The method and molecules of the present invention are useful, inter alia, in the treatment and/or prophylaxis of conditions characterised by unwanted cellular activity, such as unwanted cell survival.