Acetic acid 10-hydroxy-4-methyl-5,8-dioxo-5,8-dihydro-anthracen-2-yl ester | 144686-03-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: Acetic acid 10-hydroxy-4-methyl-5,8-dioxo-5,8-dihydro-anthracen-2-yl ester
• 英文别名: (10-Hydroxy-4-methyl-5,8-dioxoanthracen-2-yl) acetate
• CAS: 144686-03-3
• 化学式: C₁₇H₁₂O₅
• 分子量: 296.279
• InChiKey: OWPDNNLCHXUURJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  22
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  80.7
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  Chan's diene 、 Acetic acid 10-hydroxy-4-methyl-5,8-dioxo-5,8-dihydro-anthracen-2-yl ester 生成 tetracenomycin D
  参考文献：
  名称：

  Synthesis of tetracenomycins

  摘要：

  Tetracenomycins D, A2, B1 and B2 (2)-(5) have been synthesised for the first time, by an efficient, regioselective sequence based on cycloaddition methodology; the ambiguity that existed for tetracenomycins B1 and B2 has thereby been resolved in favour of structures (4a) and (5b) respectively.

  DOI：

  10.1016/s0040-4039(00)61155-3
• 作为产物：
  描述：

  quinizarin 生成 Acetic acid 10-hydroxy-4-methyl-5,8-dioxo-5,8-dihydro-anthracen-2-yl ester
  参考文献：
  名称：

  Synthesis of tetracenomycins

  摘要：

  Tetracenomycins D, A2, B1 and B2 (2)-(5) have been synthesised for the first time, by an efficient, regioselective sequence based on cycloaddition methodology; the ambiguity that existed for tetracenomycins B1 and B2 has thereby been resolved in favour of structures (4a) and (5b) respectively.

  DOI：

  10.1016/s0040-4039(00)61155-3

文献信息

• Synthesis of tetracenomycins
  作者：Donald W. Cameron、Pauline J. de Bruyn

  DOI：10.1016/s0040-4039(00)61155-3

  日期：1992.9

  Tetracenomycins D, A2, B1 and B2 (2)-(5) have been synthesised for the first time, by an efficient, regioselective sequence based on cycloaddition methodology; the ambiguity that existed for tetracenomycins B1 and B2 has thereby been resolved in favour of structures (4a) and (5b) respectively.