Gantacurium chloride | 213998-46-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异喹啉及其衍生物
• 英文名称: Gantacurium chloride
• 英文别名: 4-O-[3-[(1S,2R)-6,7-dimethoxy-2-methyl-1-(3,4,5-trimethoxyphenyl)-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propyl] 1-O-[3-[(1R,2S)-6,7-dimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl]-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propyl] (Z)-2-chlorobut-2-enedioate;dichloride
• CAS: 213998-46-0
• 化学式: C53H69Cl3N2O14
• 分子量: 1064.5
• InChiKey: SDIFKXLSGXCGEN-WJUBNSBASA-L

计算性质

• 辛醇/水分配系数(LogP)：
  1.85
• 重原子数：
  72
• 可旋转键数：
  25
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  145
• 氢给体数：
  0
• 氢受体数：
  16

反应信息

• 作为产物：
  描述：

  (1S,2R)-6,7-dimethoxy-2-(3-hydroxypropyl)-2-methyl-1-(3,4,5-trimethoxyphenyl)-1,2,3,4-tetrahydroisoquinolinium chloride 、 在 (1S,2R)-6,7-dimethoxy-2-(3-hydroxypropyl)-2-methyl-1-(3,4,5-trimethoxyphenyl)-1,2,3,4-tetrahydroisoquinolinium chloride 作用下， 以84的产率得到Gantacurium chloride
  参考文献：
  名称：

  Org Lett. 1999, 1, 1993-1996

  摘要：

  DOI：

文献信息

• NOVEL COLORED SOLUTIONS OF INJECTABLE DRUGS AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS
  申请人：Winch Peter D.

  公开号：US20090156562A1

  公开（公告）日：2009-06-18

  The invention is directed to pharmaceutical compositions comprising colored solutions, colored emulsions, or colored powders of injectable pharmaceuticals wherein said pharmaceuticals are selected from the group consisting of muscle relaxants, hypnotics, induction agents, and anticholinergics. The formulations of the present invention may all be colored using fluorescein. Different colors may be achieved by either varying the concentration of fluorescein, or by combining fluorescein with another dye. The invention is also directed to methods involving the use of said pharmaceutical compositions.
• Org Lett. 1999, 1, 1993-1996
  作者：

  DOI：——

  日期：——