3-[(2S)-1-甲基-2-吡咯烷基]吡啶2-羟基-1,2,3-丙烷三羧酸盐(1:2) | 88660-51-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 中文名称: 3-[(2S)-1-甲基-2-吡咯烷基]吡啶2-羟基-1,2,3-丙烷三羧酸盐(1:2)
• 中文别名: S-(2-溴乙基)-L-半胱氨酸
• 英文名称: (S)-Nicotine dicitrate
• 英文别名: 2-hydroxypropane-1,2,3-tricarboxylic acid;3-[(2S)-1-methylpyrrolidin-2-yl]pyridine
• CAS: 88660-51-9
• 化学式: C22H30N2O14
• 分子量: 546.5
• InChiKey: RLNVFOZAFUJKJH-XRIOVQLTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.65
• 重原子数：
  38
• 可旋转键数：
  11
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  280
• 氢给体数：
  8
• 氢受体数：
  16

文献信息

• NICOTINE SALTS AND METHODS OF MAKING AND USING SAME
  申请人：Nude Nicotine, Inc.

  公开号：EP3644771A1

  公开（公告）日：2020-05-06
• Nicotine Salts and Methods of Making and Using Same
  申请人：Nude Nicotine, Inc.

  公开号：US20200315241A1

  公开（公告）日：2020-10-08

  The present invention provides for compositions including nicotine salts, solutions thereof, methods of manufacture and methods of use. Certain embodiments provide for the delivery of said compositions including by: transdermal, oral, nasal and inhalation modes. Certain embodiments provide nicotine salts and solutions thereof, suitable for or packaged in or with devices including: oral lozenges, chewing gum, transdermal patches, intranasal sprays and intranasal inhalers, e-liquids and e-cigarette or vaping devices.
• [EN] NICOTINE SALTS AND METHODS OF MAKING AND USING SAME<br/>[FR] SELS DE NICOTINE ET PROCÉDÉS POUR LES PRÉPARER ET LES UTILISER
  申请人：NUDE NICOTINE INC

  公开号：WO2019005889A1

  公开（公告）日：2019-01-03

  The present invention provides for compositions including nicotine salts, solutions thereof, methods of manufacture and methods of use. Certain embodiments provide for the delivery of said compositions including by: transdermal, oral, nasal and inhalation modes. Certain embodiments provide nicotine salts and solutions thereof, suitable for or packaged in or with devices including: oral lozenges, chewing gum, transdermal patches, intranasal sprays and intranasal inhalers, e- liquids and e-cigarette or vaping devices.