2,6-Di-tert-butyl-benzonitrile | 154532-35-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,6-Di-tert-butyl-benzonitrile
• 英文别名: 2,6-Bis(1,1-dimethylethyl)benzonitrile；2,6-ditert-butylbenzonitrile
• CAS: 154532-35-1
• 化学式: C₁₅H₂₁N
• 分子量: 215.338
• InChiKey: HAQFEXPNKKOQDE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  23.8
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1,3-二-叔丁基-2-甲氧基苯 、 氰化钠 以 甲醇 为溶剂， 以41%的产率得到4-Methoxy-3.5-di-tert-butyl-benzonitril
  参考文献：
  名称：

  Yoshida, Kunihisa; Takeda, Kazusada; Fueno, Takayuki, Journal of the Chemical Society. Perkin transactions I, 1993, # 24, p. 3095 - 3098

  摘要：

  DOI：

文献信息

• RESIN COMPOSITION, PREPREG, METAL FOIL-TIGHTENED LAMINATED SHEET, RESIN SHEET, AND PRINTED WIRING BOARD
  申请人：MITSUBISHI GAS CHEMICAL COMPANY, INC.

  公开号：EP3805293A1

  公开（公告）日：2021-04-14

  Provided are a resin composition that can form a printed wiring board with a low dielectric constant and dielectric loss tangent and excellent alkali resistance and desmear resistance; and a prepreg, a resin sheet, a metal foil-clad laminate, and a printed wiring board formed using this resin composition. The resin composition contains a styrene-based elastomer (A), a styrene oligomer (B), a maleimide compound (C), and a cyanate ester compound (D).

  本发明提供了一种树脂组合物，该树脂组合物可以形成具有低介电常数和介电损耗正切、优异的耐碱性和抗剥落性的印刷线路板；以及使用该树脂组合物形成的预浸料、树脂片材、金属箔包覆层压板和印刷线路板。该树脂组合物包含苯乙烯基弹性体（A）、苯乙烯低聚物（B）、马来酰亚胺化合物（C）和氰酸酯化合物（D）。
• RESIN COMPOSITION, PREPREG, METAL FOIL-CLAD LAMINATE, RESIN SHEET AND PRINTED WIRING BOARD
  申请人：MITSUBISHI GAS CHEMICAL COMPANY, INC.

  公开号：EP3805316A1

  公开（公告）日：2021-04-14

  A resin composition contains a maleimide compound (A), a cyanate ester compound (B), a polyphenylene ether compound (C) with a number average molecular weight of not lower than 1000 and not higher than 7000 and represented by Formula (1), and a block copolymer (D) having a styrene backbone. In Formula (1), X represents an aryl group; -(Y-O)n2- represents a polyphenylene ether moiety; R1, R2, and R3 each independently represent a hydrogen atom, an alkyl group, an alkenyl group, or an alkynyl group; n2 represents an integer of from 1 to 100; n1 represents an integer of from 1 to 6; and n3 represents an integer of from 1 to 4.

  一种树脂组合物含有马来酰亚胺化合物 (A)、氰酸酯化合物 (B)、平均分子量不低于 1000 但不高于 7000 且由式 (1) 表示的聚苯醚化合物 (C) 和具有苯乙烯骨架的嵌段共聚物 (D)。在式 (1) 中，X 代表芳基；-(Y-O)n2- 代表聚苯醚分子；R1、R2 和 R3 各自独立地代表氢原子、烷基、烯基或炔基；n2 代表 1 至 100 的整数；n1 代表 1 至 6 的整数；n3 代表 1 至 4 的整数。
• Aromatic acetylene or aromatic ethylene compound, intermediate, preparation method, pharmaceutical composition and use thereof
  申请人：GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD.

  公开号：US11078192B2

  公开（公告）日：2021-08-03

  Disclosed are an aromatic acetylene or aromatic ethylene compound, an intermediate, a preparation method, a pharmaceutical composition and a use thereof. The aromatic acetylene or aromatic ethylene compound has a significant inhibitory effect on PD-1 and PD-L1, and can effectively relieve or treat cancers and other related diseases.

  本发明公开了一种芳香族乙炔或芳香族乙烯化合物、一种中间体、一种制备方法、一种药物组合物及其用途。芳香炔或芳香乙烯化合物对 PD-1 和 PD-L1 有显著的抑制作用，能有效缓解或治疗癌症及其他相关疾病。
• AROMATIC ACETYLENE OR AROMATIC ETHYLENE COMPOUND, INTERMEDIATE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF
  申请人：GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD.

  公开号：US20190308957A1

  公开（公告）日：2019-10-10

  Disclosed are an aromatic acetylene or aromatic ethylene compound, an intermediate, a preparation method, a pharmaceutical composition and a use thereof. The aromatic acetylene or aromatic ethylene compound has a significant inhibitory effect on PD-1 and PD-L1, and can effectively relieve or treat cancers and other related diseases.
• Resin Composition, Prepreg, Metal Foil-Clad Laminate, Resin Sheet, and Printed Wiring Board
  申请人：Mitsubishi Gas Chemical Company, Inc.

  公开号：US20210214547A1

  公开（公告）日：2021-07-15

  A resin composition contains a maleimide compound (A), a cyanate ester compound (B), a polyphenylene ether compound (C) with a number average molecular weight of not lower than 1000 and not higher than 7000 and represented by Formula (1), and a block copolymer (D) having a styrene backbone. In Formula (1), X represents an aryl group; —(Y—O)n 2 - represents a polyphenylene ether moiety; R 1 , R 2 , and R 3 each independently represent a hydrogen atom, an alkyl group, an alkenyl group, or an alkynyl group; n 2 represents an integer of from 1 to 100; n 1 represents an integer of from 1 to 6; and n 3 represents an integer of from 1 to 4.