Antrodin D | 656832-04-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: Antrodin D
• 英文别名: (3S,4R)-1-hydroxy-3-[4-(3-methylbut-2-enoxy)phenyl]-4-(2-methylpropyl)pyrrolidine-2,5-dione
• CAS: 656832-04-1
• 化学式: C₁₉H₂₅NO₄
• 分子量: 331.4
• InChiKey: ZZKUVVFNFOKVQE-IAGOWNOFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  24
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  66.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• COMPOUNDS FROM ANTRODIA CINNAMOMEA AND USE THEREOF
  申请人：SIMPSON BIOTECH CO., LTD.

  公开号：US20130225649A1

  公开（公告）日：2013-08-29

  The present invention relates to compounds from Antrodia cinnamomea . The present invention also relates to a composition and a method for treating or prophylaxis of hepatitis C virus (HCV) or human immunodeficiency virus (HIV) infection.

  本发明涉及来自红树菇的化合物。本发明还涉及一种用于治疗或预防丙型肝炎病毒（HCV）或人类免疫缺陷病毒（HIV）感染的组合物和方法。
• Novel mixture and compounds from mycelia of Antrodia camphorata and use thereof
  申请人：Hattori Masao

  公开号：US20050197384A1

  公开（公告）日：2005-09-08

  The present invention relates to novel mixture and maleic and succinic acid derivatives from mycelium of Antrodia Camphorata and the medical use thereof. The present invention relates to the composition or mycelium comprising the compounds of the invention.

  本发明涉及从樟芝菌丝体中获得的马来酸和琥珀酸衍生物的新混合物及其医药用途。本发明涉及包括本发明化合物的菌丝体组合物。
• Uses of compounds and mixtures from antrodia cinnamomea mycelia
  申请人：Simpson Biotech Co., Ltd.

  公开号：EP2878294A1

  公开（公告）日：2015-06-03

  The present invention relates to novel uses of compounds from Antrodia cinnamomea mycelia and mixtures comprising the compounds. The novel uses comprise whitening skin, combating skin ageing, reducing scar formation, inducing or enhancing liver regeneration, or treating fibrosis or a fibrosis-associated disorder in a subject in need thereof. The compounds have the formula and preferably are selected from 3-isobutyl-4-[4-(3-methyl-2-butenyloxy)phenyl]furan-2,5-dione, 3-isobutyl-4-[4-(3-methyl-2-butenyloxy)phenyl]-1H-pyrrol-2,5-dione, 3-isobutyl-4-[4-(3-methyl-2-butenyloxy)phenyl]-1H-pyrrol-1-ol-2,5-dione, 3R*,4S*-1-hydroxy-3-isobutyl-4-[4-(3-methyl-2-butenyloxy)phenyl]pyrrolidine-2 ,5-dione, and 3R*,4R*-1-hydroxy-3-isobutyl-4-[4-(3-methyl-2-butenyloxy)phenyl]pyrrolidine-2 ,5-dione.

  本发明涉及来自肉桂苣苔菌丝体的化合物和包含这些化合物的混合物的新用途。这些新型用途包括美白皮肤、抗皮肤老化、减少疤痕形成、诱导或增强肝脏再生，或治疗有需要的受试者的纤维化或纤维化相关疾病。这些化合物的化学式为 优选选自 3-isobutyl-4-[4-(3-methyl-2-butenyloxy)phenyl]furan-2,5-dione, 3-isobutyl-4-[4-(3-methyl-2-butenyloxy)phenyl]-1H-pyrrol-2,5-dione, 3-isobutyl-4-[4-(3-methyl-2-butenyloxy)phenyl]-1H-pyrrol-1-ol-2,5-dione, 3R*,4S*-1-hydroxy-3-isobutyl-4-[4-(3-methyl-2-butenyloxy)phenyl]pyrrolidine-2 ,5-dione, and 3R*,4R*-1-hydroxy-3-isobutyl-4-[4-(3-methyl-2-butenyloxy)phenyl]pyrrolidine-2 ,5-dione.
• Novel mixture and compounds from mycelia of antrodia camphorata and use thereof
  申请人：Hattori Masao

  公开号：US20060099222A1

  公开（公告）日：2006-05-11

  The present invention relates to novel mixtures and maleic and succinic acid derivatives from mycelium of Antrodia camphorata and the medical use thereof. The present invention relates to the composition or mycelium comprising the compounds of the invention.

  本发明涉及从樟芝菌丝体中提取的新型混合物以及马来酸和琥珀酸衍生物。 樟芝菌丝体 及其医疗用途。本发明涉及包含本发明化合物的组合物或菌丝体。
• JP2005247724A
  申请人：——

  公开号：JP2005247724A

  公开（公告）日：2005-09-15