Pyridinium, 1,1'-(1,6-hexanediyl)bis[4-(1,1-dimethylethyl)- | 87414-57-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: Pyridinium, 1,1'-(1,6-hexanediyl)bis[4-(1,1-dimethylethyl)-
• 英文别名: 4-tert-butyl-1-[6-(4-tert-butylpyridin-1-ium-1-yl)hexyl]pyridin-1-ium
• CAS: 87414-57-1
• 化学式: C24H38N2+2
• 分子量: 354.6
• InChiKey: MJOOYCYKVGRRID-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  26
• 可旋转键数：
  9
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  7.8
• 氢给体数：
  0
• 氢受体数：
  0

文献信息

• Pharmaceutical compositions for the treatment of organophosphate poisoning
  申请人：Wetherell Ruth Janet

  公开号：US20070093518A1

  公开（公告）日：2007-04-26

  A pharmaceutical composition comprising (i) a carbamate; (ii) a first anticholinergic; (iii) a second anticholinergic; and (iv) a pyridinium salt. The pharmaceutical composition is suitable for the treatment of organophosphate poisoning, including nerve agent and pesticide poisoning. The pharmaceutical composition provides an effective therapy against the lethal effects of nerve agent, provides effective protection from the effects of incapacitation and does not require the use of a pre-treatment. A kit comprising the pharmaceutical composition is also described and claimed.