Benzenecarboximidamide, 4,4'-(2,4-thiophenediyl)bis- | 648417-96-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benzenecarboximidamide, 4,4'-(2,4-thiophenediyl)bis-
• 英文别名: 4-[4-(4-carbamimidoylphenyl)thiophen-2-yl]benzenecarboximidamide
• CAS: 648417-96-3
• 化学式: C₁₈H₁₆N₄S
• 分子量: 320.4
• InChiKey: UYPLKQKDGJVOME-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  128
• 氢给体数：
  4
• 氢受体数：
  3

文献信息

• COMBINATIONS OF DRUGS FOR THE TREATMENT OF NEOPLASMS
  申请人：Combinatorx, Incorporated

  公开号：EP1545544A2

  公开（公告）日：2005-06-29
• COMBINATION OF DRUGS FOR THE TREATMENT OF NEOPLASMS
  申请人：CombinatoRx, Incorporated

  公开号：EP1651211A2

  公开（公告）日：2006-05-03
• EP1651211A4
  申请人：——

  公开号：EP1651211A4

  公开（公告）日：2006-11-22
• Combinations of drugs for the treatment of neoplasms
  申请人：——

  公开号：US20040116407A1

  公开（公告）日：2004-06-17

  The invention features a method for treating a patient having a cancer or other neoplasm by administering to the patient two compounds simultaneously or within 14 days of each other in amounts sufficient to treat the patient.
• Formulations, conjugates, and combinations of drugs for the treatment of neoplasms
  申请人：Nichols James M.

  公开号：US20050080075A1

  公开（公告）日：2005-04-14

  The invention provides formulations and structural modifications for phenothiazine compounds which result in altered biodistributions, thereby reducing the occurrence of adverse reactions associated with this class of drug.