1-(3-Chloro-5-fluoropyridin-2-YL)ethanone | 1256819-31-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 1-(3-Chloro-5-fluoropyridin-2-YL)ethanone
• 英文别名: 1-(3-chloro-5-fluoropyridin-2-yl)ethanone
• CAS: 1256819-31-4
• 化学式: C₇H₅ClFNO
• 分子量: 173.57
• InChiKey: IGLWAPFTHWPGCA-UHFFFAOYSA-N

物化性质

• 沸点：
  188.1±35.0 °C(Predicted)
• 密度：
  1.331±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  30
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS
  申请人：Enanta Pharmaceuticals, Inc.

  公开号：US20170022221A1

  公开（公告）日：2017-01-26

  The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Respiratory Syncytial Virus (RSV). The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from RSV infection. The invention also relates to methods of treating an RSV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
• US9957281B2
  申请人：——

  公开号：US9957281B2

  公开（公告）日：2018-05-01