3-亚磺基苯甲酸 | 15451-00-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 3-亚磺基苯甲酸
• 英文名称: m-Carboxy-benzolsulfinsaeure
• 英文别名: 3-Sulfinobenzoic acid
• CAS: 15451-00-0
• 化学式: C₇H₆O₄S
• 分子量: 186.188
• InChiKey: UZEGQEQFRRYLRK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  93.8
• 氢给体数：
  2
• 氢受体数：
  5

安全信息

• 海关编码：
  2930909090

反应信息

• 作为反应物：
  描述：

  3-亚磺基苯甲酸 在 乙醇 、 硫酸 、 水 、 氢碘酸 、 4-甲苯硫酚 作用下， 生成 3-p-tolyldisulfanyl-benzoic acid
  参考文献：
  名称：

  Smiles; Gibson, Journal of the Chemical Society, 1924, vol. 125, p. 181

  摘要：

  DOI：
• 作为产物：
  描述：

  3-氯磺酰苯甲酰氯 在 sodium sulfite 作用下， 生成 3-亚磺基苯甲酸
  参考文献：
  名称：

  Davis; Smiles, Journal of the Chemical Society, 1910, vol. 97, p. 1296

  摘要：

  DOI：

文献信息

• [EN] NEW FYN AND VEGFR2 KINASE INHIBITORS<br/>[FR] NOUVEAUX INHIBITEURS DE KINASES FYN ET VEGFR2
  申请人：ROTTAPHARM BIOTECH SRL

  公开号：WO2021115560A1

  公开（公告）日：2021-06-17

  The invention relates to a N-phenylcarbamoyl compound of Formula (I) or a pharmaceutically acceptable salt thereof for use in the inhibition of at least one of tyrosine kinase selected from Fyn and VEGFR2 in the treatment of diseases and disorders involved with one or both kinases. (Formula)

  该发明涉及一种化合物N-苯基甲酰胺（I）的使用或其在治疗涉及Fyn和VEGFR2中至少一种酪氨酸激酶抑制剂中的药用盐，用于治疗与这两种激酶中至少一种相关的疾病和疾病。
• Chemical compounds
  申请人：——

  公开号：US20040102432A1

  公开（公告）日：2004-05-27

  The invention provides compounds of formula (I): as modulators of chemokine and H1 receptor activity. The compounds are especially useful in the treatment of asthma and rhinitis.

  该发明提供了化合物的公式（I）：作为趋化因子和H1受体活性的调节剂。这些化合物在哮喘和鼻炎的治疗中特别有用。
• Polyhalogenomethylsulfonyl compound
  申请人：Fuji Photo Film Co., Ltd.

  公开号：US20020018955A1

  公开（公告）日：2002-02-14

  ? The object of the present invention is to provides a novel polyhalogenomethylsulfonyl compound which can be used for providing a thermally processed image recording material which has a high sensitivity, gives less fog, and has a good stock stability and a good image storage stability of dark and high temperature or light storage. According to the present invention, there is provided a polyhalogenomethylsulfonyl compound represented by the following formula (1), or salts thereof, or hydrates or solvates thereof: 1 wherein Z 1 and Z 2 each independently represents a halogen atom; A represents a hydrogen atom or a halogen atom; and R 1 represents an alkyl group having from 2 to 12 carbon atoms, which may have one or more substituents, an alkenyl group having from 2 to 12 carbon atoms, which may have one or more substituents, or an alkinyl group having from 2 to 12 carbon atoms, which may have one or more substituents.

  本发明的目的是提供一种新型的聚卤代甲基磺酰化合物，可用于提供具有高灵敏度、较少雾化、良好的库存稳定性和良好的暗高温或光存储稳定性的热处理图像记录材料。根据本发明，提供了由以下式（1）表示的聚卤代甲基磺酰化合物，或其盐，或其水合物或溶剂化物：其中Z1和Z2各自独立地表示卤素原子；A表示氢原子或卤素原子；R1表示具有2至12个碳原子的烷基基团，可以具有一个或多个取代基，具有2至12个碳原子的烯基基团，可以具有一个或多个取代基，或具有2至12个碳原子的炔基基团，可以具有一个或多个取代基。
• Disulfones as peroxygen activators
  申请人：FMC Corporation

  公开号：US04120651A1

  公开（公告）日：1978-10-17

  A process of removing soil and/or stains from fabrics by immersing the fabrics in a peroxygen bleach bath containing as a peroxygen activator a disulfone of the formula RSO.sub.2 SO.sub.2 R.sub.1 wherein R and R.sub.1, which may be alike or different, are each selected from the class consisting of an alkyl radical of 1 to 18 carbon atoms; a cycloalkyl radical of 3 to 7 carbon atoms said alkyl and cycloalkyl radicals bearing optional substituents selected from the group consisting of lower alkoxyl, fluoro and chloro; and an aromatic radical selected from the group consisting of phenyl, naphthyl and heterocyclic having 1 ring or 2 fused rings containing 5 to 6 members of which 1 to 2 are heteroatoms selected from the class consisting of nitrogen, oxygen and sulfur, said aromatic radicals optionally bearing 1 to 3 substituents selected from the class consisting of nitro, alkyl of 1 to 16 carbon atoms, alkoxy of 1 to 16 carbon atoms, aliphatic carboxamido of 1 to 16 carbon atoms, benzamido, chlorine and bromine. Aromatic is used herein in its modern sense to signify an organic ring system having aromatic character including both aromatic hydrocarbon and heterocyclic ring systems. Also described are dry blend compositions containing the bleach bath components.

  一种从织物中去除土壤和/或污渍的过程，通过将织物浸泡在过氧化物漂白浴中，其中包含一种二磺酸酯作为过氧化物活化剂，该二磺酸酯的化学式为RSO.sub.2 SO.sub.2 R.sub.1，其中R和R.sub.1（可能相同或不同）均选自以下类别：1至18个碳原子的烷基基团；3至7个碳原子的环烷基基团，所述烷基和环烷基基团带有可选的取代基，所述取代基选自以下群体：低级烷氧基，氟和氯；以及选自苯基，萘基和含有1个环或2个融合环的杂环基团，所述杂环基团含有5至6个成员，其中1至2个是从氮，氧和硫中选择的杂原子，所述芳基基团可选地带有1至3个取代基，所述取代基选自以下类别：1至16个碳原子的烷基，1至16个碳原子的烷氧基，1至16个碳原子的脂肪族羧酰胺基，苯甲酰胺基，氯和溴。本文中所使用的芳香族是指具有芳香性的有机环系统，包括芳香族碳氢化合物和杂环环系统。还描述了包含漂白浴组分的干混合物组合物。
• Color developing agent, processing composition and color image-forming method
  申请人：Fuji Photo Film Co., Ltd.

  公开号：EP0670312A1

  公开（公告）日：1995-09-06

  A method for forming a color image comprises the step of developing an image-wise exposed silver halide color photographic photosensitive material in the presence of a 6-aminotetrahzdroquinoline color developing agent (claimed) which is the following compound or its analogue. According to this method, the rapid process can be attained and an image of a low fog density can be obtained. Examples of the developing agent include

  一种形成彩色图像的方法包括以下步骤：在 6-氨基四氢喹啉显色剂（权利要求）（即以下化合物或其类似物）存在的情况下，对已曝光的卤化银彩色感光材料进行显影。根据这种方法，可以实现快速冲洗，并获得雾密度低的图像。 显影剂的例子包括