2-[(Pyrrolidin-1-yl)methylidene]-2H-pyrrole | 61338-84-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: 2-[(Pyrrolidin-1-yl)methylidene]-2H-pyrrole
• 英文别名: 2-(pyrrolidin-1-ylmethylidene)pyrrole
• CAS: 61338-84-9
• 化学式: C₉H₁₂N₂
• 分子量: 148.2
• InChiKey: PYWBZPSJAOZVSU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  15.6
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• TRIAZOL-1-OL ANALOGS ANTI-RETROVIRAL LATENCY DRUGS
  申请人：University of Utah Research Foundation

  公开号：EP3008043A2

  公开（公告）日：2016-04-20
• [EN] TRIAZOL-1-OL ANALOGS ANTI-RETROVIRAL LATENCY DRUGS<br/>[FR] ANALOGUES TRIAZOL-1-OL MÉDICAMENTS DE LATENCE ANTIRÉTROVIRAL
  申请人：UNIV UTAH RES FOUND

  公开号：WO2014201426A2

  公开（公告）日：2014-12-18

  In one aspect, the invention relates to triazol-1-ol compounds, analogs thereof, compositions comprising same, and methods of using same, alone or in combination with other agents, to reactivate latent retroviruses, and more particularly to reactivate latent HIV-1. Such compounds, compositions, and methods can be used, for example, in connection with diagnosing and/or treating a retrovirus, and more specifically HIV-1. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.