2,2'-[4-(Thiophen-2-yl)pyridine-2,6-diyl]bis(1-oxo-1lambda~5~-pyridine) | 600729-72-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2,2'-[4-(Thiophen-2-yl)pyridine-2,6-diyl]bis(1-oxo-1lambda~5~-pyridine)
• 英文别名: 2,6-bis(1-oxidopyridin-1-ium-2-yl)-4-thiophen-2-ylpyridine
• CAS: 600729-72-4
• 化学式: C19H13N3O2S
• 分子量: 347.4
• InChiKey: FNKPCHYJYZGCOK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  25
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  92
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• NOVEL FLUORESCENT LABEL COMPOUNDS
  申请人：Matsumoto, Kazuko

  公开号：EP1489418A1

  公开（公告）日：2004-12-22

  It is intended to provide novel labeling reagents characterized by having a group capable of binding to a substance to be labeled (for example, a biological substance, a physiologically active substance, etc.), easily forming a complex together with a rare earth ion, the complex being stable in an aqueous solution, and having a sufficient fluorescence intensity and a long fluorescence life time regardless of buffer types; complexes composed of the above labeling reagent with a rare earth ion; fluorescence labels containing the above complex; a fluorescence assaymethod using the above fluorescent label; etc. Namely, labeling reagents comprising a compound having a 2, 2' :6', 2" -tripyridine skeleton or a 2, 6-dipyrazolopyridine skeleton and having a group capable of binding to a substance to be labeled (for example, a biological substance, a physiologically active substance, etc.) and a group capable of forming a complex together with a rare earth ion; complexes composed of the above labeling reagent with a rare earth ion; fluorescence labels containing the above complex; a fluorescence labeling method using the above complex as a label; and a fluorescence assay method using the above fluorescent label.

  本发明旨在提供新型标记试剂，其特征在于：具有能够与待标记物质（例如生物物质、生理活性物质等）结合的基团，易于与稀土离子形成络合物，络合物在水溶液中稳定，并且具有足够的荧光强度和较长的荧光寿命，不受缓冲液类型的影响。其特征是：具有能够与待标记物质（例如生物物质、生理活性物质等）结合的基团，容易与稀土离子形成络合物，该络合物在水溶液中稳定，并且具有足够的荧光强度和较长的荧光寿命，不受缓冲液类型的影响；由上述标记试剂与稀土离子组成的络合物；含有上述络合物的荧光标签；使用上述荧光标签的荧光检测方法等。也就是说，标记试剂包括具有 2，2' :6'，2" -三吡啶骨架或 2，6-二吡唑吡啶骨架的化合物，该化合物具有能够与要标记的物质（例如生物物质、生理活性物质等）结合的基团，以及能够与要标记的物质（例如生物物质、生理活性物质等）结合的基团。)和能够与稀土离子形成络合物的基团；由上述标记试剂与稀土离子组成的络合物；含有上述络合物的荧光标签；使用上述络合物作为标签的荧光标记方法；以及使用上述荧光标签的荧光检测方法。
• Novel fluorescent label compounds
  申请人：Matsumoto Kazuko

  公开号：US20050255465A1

  公开（公告）日：2005-11-17

  It is intended to provide novel labeling reagents characterized by having a group capable of binding to a substance to be labeled (for example, a biological substance, a physiologically active substance, etc.), easily forming a complex together with a rare earth ion, the complex being stable in an aqueous solution, and having a sufficient fluorescence intensity and a long fluorescence life time regardless of buffer types; complexes composed of the above labeling reagent with a rare earth ion; fluorescence labels containing the above complex; a fluorescence assay method using the above fluorescent label; etc. Namely, labeling reagents comprising a compound having a 2,2′:6′,2″-tripyridine skeleton or a 2,6-dipyrazolopyridine skeleton and having a group capable of binding to a substance to be labeled (for example, a biological substance, a physiologically active substance, etc.) and a group capable of forming a complex together with a rare earth ion; complexes composed of the above labeling reagent with a rare earth ion; fluorescence labels containing the above complex; a fluorescence labeling method using the above complex as a label; and a fluorescence assay method using the above fluorescent label.

  本发明旨在提供新型标记试剂，其特征在于：具有能够与待标记物质（例如生物物质、生理活性物质等）结合的基团，易于与稀土离子形成络合物，络合物在水溶液中稳定，并且具有足够的荧光强度和较长的荧光寿命，不受缓冲液类型的影响。)，容易与稀土离子形成络合物，该络合物在水溶液中稳定，并具有足够的荧光强度和较长的荧光寿命，不受缓冲液类型的影响；由上述标记试剂与稀土离子组成的络合物；含有上述络合物的荧光标签；使用上述荧光标签的荧光检测方法等。也就是说，标记试剂包括具有 2,2′:6′,2″-三吡啶骨架或 2,6-二吡唑吡啶骨架的化合物，该化合物具有能够与待标记物质（例如生物物质、生理活性物质等）结合的基团，以及能够与待标记物质（例如生物物质、生理活性物质等）结合的基团。)和能够与稀土离子形成络合物的基团；由上述标记试剂与稀土离子组成的络合物；含有上述络合物的荧光标签；使用上述络合物作为标签的荧光标记方法；以及使用上述荧光标签的荧光检测方法。
• US7465747B2
  申请人：——

  公开号：US7465747B2

  公开（公告）日：2008-12-16