3-氨基丙基二甲基甲氧硅烷 | 31024-26-7

• 物质功能分类: 化学试剂 - 有机试剂 - 硅氧烷
• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 中文名称: 3-氨基丙基二甲基甲氧硅烷
• 中文别名: (3-氨基丙基)二甲基甲氧基硅烷
• 英文名称: (3-aminopropyl)dimethylmethoxysilane
• 英文别名: (3-aminopropyl)methoxydimethylsilane；(3-Aminopropyl)dimethylmethoxysilan；3-aminopropylmethoxyldimethylsilane；3-aminopropyldimethylmethoxysilane；APDMES；APMS；3-[methoxy(dimethyl)silyl]propan-1-amine
• CAS: 31024-26-7
• 化学式: C₆H₁₇NOSi
• mdl: MFCD01861689
• 分子量: 147.293
• InChiKey: MCLXOMWIZZCOCA-UHFFFAOYSA-N

物化性质

• 沸点：
  87 °C (50 mmHg)
• 密度：
  0.87
• 稳定性/保质期：
  稳定

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  35.2
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 危险品标志：
  Xi
• 安全说明：
  S26,S37/39
• 危险类别码：
  R36/37/38
• 海关编码：
  29319090
• 储存条件：
  请将贮藏器密封保存，并存放在阴凉干燥处。确保工作环境中具有良好通风或排气设施。

SDS

Name:	3-Aminopropyldimethylmethoxysilane 97% Material Safety Data Sheet
Synonym:	None
CAS:	31024-26-7

Section 1 - Chemical Product MSDS Name:3-Aminopropyldimethylmethoxysilane 97% Material Safety Data Sheet
Synonym:None

---

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
31024-26-7	3-Aminopropyldimethylmethoxysilane	97	unlisted

Hazard Symbols: XI
Risk Phrases: 36/37/38

---

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation. May cause conjunctivitis. May cause blindness. Contact with the eyes may cause corneal damage.
Skin:
Causes skin irritation.
Ingestion:
May cause irritation of the digestive tract. May cause headache, nausea, fatigue, and dizziness.
Inhalation:
Causes respiratory tract irritation. Can produce delayed pulmonary edema.
Chronic:
Effects may be delayed.

---

Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:
Treat symptomatically and supportively.

---

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Contact with water liberates highly flammable gases. Runoff from fire control or dilution water may cause pollution.
Extinguishing Media:
Use dry sand or earth to smother fire. Use dry chemical to fight fire.

---

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation. Do not get water on spilled substances or inside containers.

---

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use only in a chemical fume hood. Wash clothing before reuse.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture.

---

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 31024-26-7: Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

---

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Liquid
Color: clear, colorless
Odor: amine-like
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: Reacts.
Specific Gravity/Density:
Molecular Formula: C6H17NOSi
Molecular Weight: 147.29

---

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions. Material generates methanol on contact with water or moisture on the skin, eyes and mucous membranes.
Conditions to Avoid:
Excess heat, Reacts with water to form methanol. The heat of the reaction may ignite the vapor of the alcohol..
Incompatibilities with Other Materials:
Alcohols, water, strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, silicon dioxide, methanol.
Hazardous Polymerization: Has not been reported

---

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 31024-26-7 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
3-Aminopropyldimethylmethoxysilane - Not listed by ACGIH, IARC, or NTP.

---

Section 12 - ECOLOGICAL INFORMATION

---

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

---

Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

---

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 31024-26-7: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 31024-26-7 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 31024-26-7 is not listed on the TSCA inventory.
It is for research and development use only.

---

SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  草酸二甲酯 、 3-氨基丙基二甲基甲氧硅烷 反应 2.5h， 以192 g的产率得到
  参考文献：
  名称：

  SILANES COMPRISING OXAMIDO ESTER GROUPS

  摘要：

  氧胺酯官能化烷基烷氧基硅烷通过烷基烷氧基硅烷与草酸二酯的反应高产率制备。

  公开号：

  US20210079027A1
• 作为产物：
  描述：

  甲醇 、 3-[(2,2-二甲基-1,2-氮杂硅环戊烷-1-基)-(二甲基)-硅烷基]-1-丙胺 在 ice 作用下， 以 四氢呋喃 为溶剂， 以gave 28 g of aminopropyldimethylmethoxysilane (95% yield)的产率得到3-氨基丙基二甲基甲氧硅烷
  参考文献：
  名称：

  Process for preparing aminoalkysilanes

  摘要：

  通过与醇反应，从氨基烷基硅烷生产的底部高产高纯度地回收有用的产品，提高氨基烷基硅烷合成的经济性。

  公开号：

  US07459576B2

文献信息

• On the Reversible Photoisomerization of Spiropyran-Modified Zeolite L Single Crystals
  作者：R. Q. Albuquerque、J. Kühni、P. Belser、L. De Cola

  DOI：10.1002/cphc.200900860

  日期：2010.2.22

  photoisomerization of a derivative of spiropyran at the level of a single crystal by using zeolite L is demonstrated. The synthesized spiropyran exhibits rare negative photochromism when dissolved in a 1:1 mixture of H2O and EtOH The spiropyran is functionalized predominantly at the channel entrances in the case of 4 μm long crystals (see picture).

  两者兼有：证明了使用沸石L在单晶水平上螺吡喃衍生物的可逆光异构化。合成的螺吡喃溶解在H 2 O和EtOH的1：1混合物中时，表现出罕见的负光致变色现象。对于4μm长的晶体，螺吡喃主要在通道入口处被官能化（参见图片）。
• Synthesis of Novel Reactive Disperse Silicon-Containing Dyes and Their Coloring Properties on Silicone Rubbers
  作者：Ning Yu、Shufen Zhang、Bingtao Tang、Wei Ma、Jinjing Qiu

  DOI：10.3390/molecules23010127

  日期：——

  silicone reactive agents. These dyes were characterized by UV-Vis, 1H-NMR, FT-IR, and MS. The obtained reactive disperse silicon-containing dyes were used to color silicone rubbers and the color fastness of the dyes were evaluated. The dry/wet rubbing and washing fastnesses of these dyes all reached 4–5 grade and the sublimation fastness was also above 4 grade, indicating outstanding performance in terms of

  以对硝基苯胺和 6-溴-2,4-二硝基苯胺为重氮组分，氰尿酰氯与 3-(N,N-二乙基)氨基苯胺作为偶联组分，3-氨基丙基甲氧基二甲基硅烷、3-氨基丙基甲基二甲氧基硅烷和3-氨基丙基三甲氧基硅烷作为有机硅反应剂。这些染料的特征在于 UV-Vis、1H-NMR、FT-IR 和 MS。将所得活性分散含硅染料用于硅橡胶的着色，并评价染料的色牢度。这些染料的干湿摩擦牢度和水洗牢度均达到4-5级，升华牢度也在4级以上，在色牢度方面表现突出。
• METHOD FOR PREPARING AMINOPROPYLSILANES
  申请人：WACKER CHEMIE AG

  公开号：US20210284666A1

  公开（公告）日：2021-09-16

  Aminopropylalkoxysilanes of the formula H 2 N—CR 2 R 3 —CHR 1 —CH 2 —SiR 4 R 5 (OR 6 )   I, are synthesized by hydrosilylating silazanes of the formulae and mixtures thereof, in the presence of a catalyst containing rhodium and/or iridium compounds, and then reacted with alcohol to form an aminopropylalkoxysilane.

  公式为H2N—CR2R3—CHR1—CH2—SiR4R5(OR6)的氨丙基烷氧基硅烷I，是在存在含铑和/或铱化合物催化剂的情况下，通过氢硅烷化硅氮烷及其混合物的方法合成的，然后与醇反应形成氨丙基烷氧基硅烷。
• METHOD FOR PRODUCING AMINOALKYLALKOXYSILANES
  申请人：Wacker Chemie AG

  公开号：US20150051418A1

  公开（公告）日：2015-02-19

  Aminoalkylalkoxysilanes are prepared from halo(haloalkyl)silanes in the simultaneous presence of ammonia or primary organic amine and alcohol.

  Aminoalkylalkoxysilanes是从卤代（卤代烷基）硅烷在氨或初级有机胺和醇的同时存在下制备的。
• Cyclic silazanes
  申请人：Consortium fur elektrochemische Industrie GmbH

  公开号：US20020042491A1

  公开（公告）日：2002-04-11

  The invention relates to cyclic silazanes of the general formula II 1 in which R is a divalent, Si-C and Si-N-bound, optionally cyano- or halogen-substituted C 3 -C 15 -hydrocarbon radical, in which one or more, non-adjacent methylene units may be replaced by -O-, -CO-, -COO-, -OCO-, -OCOO-, -S- or -NR x - groups and in which one or more non-adjacent methine units may be replaced by -N=, -N=N- or -P= groups, where at least 3 and at most 6 atoms are arranged between the silicon atom and the nitrogen atom of the ring, R x is hydrogen or an optionally halogen-substituted C 1 -C 10 -hydrocarbon radical, and R 2 is a hydrogen atom or a monovalent, optionally cyano- or halogen-substituted, Si-C-bound C 1 -C 20 -hydrocarbon radical or C 1 -C 20 -hydrocarbonoxy radical, in each of which one or more non-adjacent methylene units may be replaced by -O-, -CO-, -COO-, -OCO-, -OCOO-, -S- or -NR x - groups and in which one or more non-adjacent methine units may be replaced by -N=, -N=N- or -P=groups.

  本发明涉及一般式II1的环状硅氮烷，其中R是一个二价的，Si-C和Si-N键合的，可选择氰基或卤素取代的C3-C15烃基，其中一个或多个不相邻的亚甲基单元可以被-O-，-CO-，-COO-，-OCO-，-OCOO-，-S-或-NRx-基团所取代，并且其中一个或多个不相邻的亚甲基单元可以被-N=，-N=N-或-P=基团所取代，在硅原子和环的氮原子之间至少有3个至多6个原子排列，Rx是氢或一个可选的卤素取代的C1-C10烃基，R2是氢原子或一个单价的，可选择氰基或卤素取代的Si-C键合的C1-C20烃基或C1-C20烃氧基，其中一个或多个不相邻的亚甲基单元可以被-O-，-CO-，-COO-，-OCO-，-OCOO-，-S-或-NRx-基团所取代，并且其中一个或多个不相邻的亚甲基单元可以被-N=，-N=N-或-P=基团所取代。