Octyltrichlorosilane is a colorless liquid with a pungent odor. It is decomposed by water to hydrochloric acid with evolution of heat. It is corrosive to metals and tissue. It is used as an intermediate for silicones.
颜色/状态：
Fuming liquid
气味：
Pungent, irritating odor
溶解度：
Soluble in carbon tetrachloride
分解：
The silanes decomp at elevated temp to liberate hydrogen and deposit a high purity silicon, which leads to some of the principal uses of silanes. /Silanes/
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Silane, Chlorosilane, and Related Compounds/
Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Anticipate seizures and treat if necessary ... . Monitor for shock and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal (refer to ingestion protocol in Section Three ... . Cover skin burns with sterile dressings after decontamination ... . /Silane, Chlorosilane, and Related Compounds/
Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Early intubation at the first sign of upper airway obstruction may be necessary. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors if patient is hypotensive with a normal fluid volume. Watch for signs of fluid overload ... . Treat seizures with diazepam or lorazepam ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Silane, Chlorosilane, and related compounds/
/SIGNS AND SYMPTOMS/ Acute inhalation exposure may result in sneezing, choking, laryngitis, dyspnea (shortness of breath), respiratory tract irritation, and chest pain. Higher exposure can cause pulmonary edema, a medical emergency that can be delayed for several hours. This can cause death. Bleeding of nose and gums, ulceration of the nasal and oral mucosa, pulmonary edema, chronic bronchitis, and pneumonia may also occur. If the eyes have come in contact with dimethyldichlorosilane, irritation, pain, swelling, corneal erosion, and blindness may result. Dermatitis (red, inflamed skin), severe burns, pain, and shock generally follow dermal exposure. Inhalation irritates mucous membranes. Severe gastrointestinal damage may occur. Vapors cause severe eye and lung injury. Upon short contact, second and third degree burns may occur. Signs and symptoms of acute ingestion of dimethyldichlorosilane may be severe and include increased salivation, intense thirst, difficulty swallowing, chills, pain, and shock. Oral, esophageal, and stomach burns are common. /Dimethyldichlorosilane/
PROCESS FOR PREPARING ORGANOCHLOROSILANES BY DEHYDROHALOGENATIVE COUPLING REACTION OF ALKYL HALIDES WITH CHLOROSILANES
申请人：——
公开号：US20020082438A1
公开（公告）日：2002-06-27
The present invention relates to a process for preparing organochlorosilanes and more particularly, to the process for preparing organochlorosilanes of formula I by a dehydrohalogenative coupling of hydrochlorosilanes of formula II with organic halides of formula III in the presence of quaternary phosphonium salt as a catalyst to provide better economical matter and yield compared with conventional methods, because only catalytic amount of phosphonium chloride is required and the catalyst can be separated from the reaction mixture and recycled easily,
1
wherein
R
1
represents hydrogen, chloro, or methyl;
X represents chloro or bromo;
R
2
is selected from the group consisting of C
1-17
alkyl, C
1-10
fluorinated alkyl with partial or full fluorination, C
2-5
alkenyl, silyl containing alkyl group represented by (CH
2
)
n
SiMe
3-m
Cl
m
wherein n is an integer of 0 to 2 and m is an integer of 0 to 3, aromatic group represented by Ar(R′)
q
wherein Ar is C
6-14
aromatic hydrocarbon, R′ is C
1-4
alkyl, halogen, alkoxy, or vinyl, and q is an integer of 0 to 5, haloalkyl group represented by (CH
2
)
p
X wherein p is an integer of 1 to 9 and X is chloro or bromo, and aromatic hydrocarbon represented by ArCH
2
X wherein Ar is C
6-14
aromatic hydrocarbons and X is a chloro or bromo;
R
3
is hydrogen, C
1-6
alkyl, aromatic group represented by Ar(R′)
q
wherein Ar is C
6-14
aromatic hydrocarbon, R′ is C
1-4
alkyl, halogen, alkoxy, or vinyl, and q is an integer of 0 to 5; and
R
4
in formula I is the same as R
2
in formula III and further, R
4
can also be (CH
2
)
p
SiR
1
Cl
2
or ArCH
2
SiR
1
Cl
2
, when R
2
in formula III is (CH
2
)
p
X or ArCH
2
X, which is formed from the coupling reaction of X—(CH
2
)
p+1
—X or XCH
2
ArCH
2
X with the compounds of formula II; or
when R
2
and R
3
are covalently bonded to each other to form a cyclic compounds of cyclopentyl or cyclohexyl group, R
3
and R
4
are also covalently bonded to each other in the same fashion.
本发明涉及一种制备有机氯硅烷的方法，更具体地说，涉及一种通过在四元磷盐存在下，将式II的氯硅烷与式III的有机卤化物脱卤偶联以制备式I的有机氯硅烷的方法，与传统方法相比，该方法提供了更好的经济性和产量，因为只需要催化量的磷盐氯化物，并且催化剂可以从反应混合物中分离并轻松回收，
其中
R
1
代表氢、氯或甲基；
X代表氯或溴；
R
2
选自由C
1-17
烷基、C
1-10
部分或全氟化的氟烷基、C
2-5
烯基、含有(CH
2
)
n
SiMe
3-m
Cl
m
的硅基烷基，其中n为0至2的整数，m为0至3的整数，由Ar(R′)
q
表示的芳香族，其中Ar为C
6-14
芳香烃，R′为C
1-4
烷基、卤素、烷氧基或乙烯基，q为0至5的整数，由(CH
2
)
p
X表示的卤代烷基，其中p为1至9的整数，X为氯或溴，以及由ArCH
2
X表示的芳香烃，其中Ar为C
6-14
芳香烃，X为氯或溴；
R
3
为氢、C
1-6
烷基、由Ar(R′)
q
表示的芳香族，其中Ar为C
6-14
芳香烃，R′为C
1-4
烷基、卤素、烷氧基或乙烯基，q为0至5的整数；以及
式I中的R
4
与式III中的R
2
相同，此外，当式III中的R
2
为(CH
2
)
p
X或ArCH
2
X时，R
4
还可以是(CH
2
)
p
SiR
1
Cl
2
或ArCH
2
SiR
1
Cl
2
，其中R
2
在式III中为(CH
2
)
p
X或ArCH
2
X，它由X—(CH
2
)
p+1
—X或XCH
2
ArCH
2
X与式II的化合物的偶联反应形成；或
当R
2
和R
3
以共价键结合形成环戊基或环己基化合物时，R
3
和R
4
也以相同方式共价键结合。
Process for preparing organochlorosilanes by dehydrohalogenative coupling reaction of alkyl halides with chlorosilanes
申请人：Korea Institute of Science and Technology
公开号：US06392077B1
公开（公告）日：2002-05-21
The present invention relates to a process for preparing organochlorosilanes and more particularly, to the process for preparing organochlorosilanes of R4R3CHSiR1Cl2 (I) by a dehydrohalogenative coupling of hydrochlorosilanes of HSiR1Cl2 (II) with organic halides of R2R3 CHX (III) in the presence of quaternary phosphonium salt as a catalyst to provide better economical matter and yield compared with conventional methods, because only a catalytic amount of phosphonium chloride is required and the catalyst can be separated from the reaction mixture and recycled easily.
[EN] PROCESS FOR THE STEPWISE SYNTHESIS OF SILAHYDROCARBONS<br/>[FR] PROCÉDÉ DE SYNTHÈSE SÉQUENTIELLE DE SILAHYDROCARBURES
申请人：MOMENTIVE PERFORMANCE MAT INC
公开号：WO2021243137A1
公开（公告）日：2021-12-02
The invention relates to a process for the stepwise synthesis of silahydrocarbons bearing up to four different organyl substituents at the silicon atom, wherein the process includes at least one step a) of producing a bifunctional hydridochlorosilane by a redistribution reaction, selective chlorination of hydridosilanes with an ether/HCI reagent, or by selective chlorination of hydridosilanes with SiCI4, at least one step b) of submitting a bifunctional hydridochloromonosilane to a hydrosilylation reaction, at least one step c) of hydrogenation of a chloromonosilane, and a step d) in which a silahydrocarbon compound is obtained in a hydrosilylation reaction.
本发明涉及一种逐步合成在硅原子上带有最多四种不同有机基团取代的硅氢化物的过程，其中该过程包括至少以下步骤：a) 通过重分配反应、使用醚/HCI试剂对氢硅烷进行选择性氯化，或者通过使用四氯化硅对氢硅烷进行选择性氯化来制备双功能氢氯硅烷；至少一个步骤 b) 将双功能氢氯单硅烷进行氢硅化反应；至少一个步骤 c) 对氯代单硅烷进行氢化；以及步骤 d) 在氢硅化反应中获得硅氢化物化合物。
Oxidative cleavage of silicon-carbon bonds in organosilicon fluorides to alcohols
Certain functional silyi groups have been shown to be synthetically equivalent to the OH group. All of the C-Si bonds in organosilicon fluorides, K2(RSiF5] and RnSiF4-n, (n = 1,2,3) are cleaved by m-chloroperbenzoic acid (MCPBA) in DMF to give the corresponding alcohols in high yields. Although the reaction with RSiF52- and RSiF3 proceeds without any additive, cleavage of R2SiF2 and R3SiF requires
