Bis[(2-oxo-1,3-oxazolidin-3-yl)]phosphinic bromide | 90429-06-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: Bis[(2-oxo-1,3-oxazolidin-3-yl)]phosphinic bromide
• 英文别名: 3-[bromo-(2-oxo-1,3-oxazolidin-3-yl)phosphoryl]-1,3-oxazolidin-2-one
• CAS: 90429-06-4
• 化学式: C₆H₈BrN₂O₅P
• 分子量: 299.02
• InChiKey: GDTLGNAJDACRQG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  76.2
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• [EN] PREPARATION OF CHEMICALLY WELL-DEFINED CARBOHYDRATE DENDRIMER CONJUGATES<br/>[FR] PREPARATION DE CONJUGUES DE DENDRIMERE ET DE GLUCIDE CHIMIQUEMENT BIEN DEFINIS
  申请人：DANMARKS FOEDEVARE OG VETERINA

  公开号：WO2004041310A1

  公开（公告）日：2004-05-21

  A method for the synthesis of dendrimer conjugates having a well-defined chemical structure, comprising one or more carbohydrate moieties and one or more immunomodulating substances coupled to a dendrimer, is presented. First, the carbohydrate is bound to the dendrimer in a chemoselective manner. Subsequently, the immunomodulating substance is also bound in a chemoselective manner, to give a dendrimer conjugate with a well-defined structure and connectivity and containing a precise, pre-determined ratio of carbohydrate to immunomodulating substance. The invention also relates to novel dendrimer conjugates and their use in vaccination, production of antibodies, high throughput screening, diagnostic assays and libraries.