Benzyl 3-hydroxy-3-vinylazetidine-1-carboxylate | 1356109-31-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benzyl 3-hydroxy-3-vinylazetidine-1-carboxylate
• 英文别名: benzyl 3-ethenyl-3-hydroxyazetidine-1-carboxylate
• CAS: 1356109-31-3
• 化学式: C₁₃H₁₅NO₃
• 分子量: 233.26
• InChiKey: NQJLLPYHZDUTIL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  49.8
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• [EN] SUBSTITUTED PYRAZOLOPYRIMIDINES AS IRAK4 INHIBITORS<br/>[FR] PYRAZOLOPYRIMIDINES SUBSTITUÉES EN TANT QU'INHIBITEURS D'IRAK4
  申请人：BAYER AG

  公开号：WO2021064077A1

  公开（公告）日：2021-04-08

  The present application relates to novel pyrazolopyrimidine derivatives for treatment and/or prophylaxis of diseases and to the use thereof for production of medicaments f or treatment and/or prophylaxis of diseases in humans and in animals, especially of proliferative disorder, autoimmune disorder, metabolic or inflammatory disorder characterized by an overreacting immune system, in particular rheumatological disorder, inflammatory skin disorder, cardiovascular disorder, lung disorder, kidney disorder, eye disorder, neurological disorder, pain disorder and cancer, in human as well as of allergic and/or inflammatory diseases in animals, especially of atopic dermatitis and/or Flea Allergy Dermatitis, and especially in domestic animals, particularly in dogs.