4-Bromo-2,3-difluoro-N-methyl-6-nitroaniline | 1381944-44-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-Bromo-2,3-difluoro-N-methyl-6-nitroaniline
• CAS: 1381944-44-0
• 化学式: C7H5BrF2N2O2
• 分子量: 267.03
• InChiKey: FXWJIGIKWQZDQR-UHFFFAOYSA-N

物化性质

• 沸点：
  307.7±42.0 °C(Predicted)
• 密度：
  1.837±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  57.8
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE
  申请人：PTC Therapeutics, Inc.

  公开号：EP3773552A1

  公开（公告）日：2021-02-17
• [EN] COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE<br/>[FR] COMPOSÉS PERMETTANT DE TRAITER LA MALADIE DE HUNTINGTON
  申请人：PTC THERAPEUTICS INC

  公开号：WO2019191229A1

  公开（公告）日：2019-10-03

  The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I) or Formula (II), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.