Arformoterol maleate | 1254575-18-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Arformoterol maleate
• 英文别名: (Z)-but-2-enedioic acid;N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino]ethyl]phenyl]formamide
• CAS: 1254575-18-2
• 化学式: C23H28N2O8
• 分子量: 460.5
• InChiKey: ZDUPYZMAPCZGJO-QVVSPZKGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.94
• 重原子数：
  33
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  165
• 氢给体数：
  6
• 氢受体数：
  9

文献信息

• PHARMACEUTICAL AEROSOL FORMULATIONS OF FORMOTEROL AND BECLOMETASONE DIPROPIONATE
  申请人：BRAMBILLA Gaetano

  公开号：US20110081301A1

  公开（公告）日：2011-04-07

  Pharmaceutical formulations comprising beclometasone dipropionate and a salt of formoterol exhibit improved stability and are useful in pressurised metered dose inhalers (pMDIs).
• CONTROLLED-RELEASE MICROPARTICLES AND METHOD OF PREPARING SAME
  申请人：Shin Kwang-Hyun

  公开号：US20110217371A1

  公开（公告）日：2011-09-08

  Disclosed is a controlled-release microparticle: including a matrix comprising a pharmacologically active component; and a controlled-release layer comprising a substance which forms a controlled-release stratum on the matrix. The disclosed controlled-release microparticle not only allows effective dual release control of a drug but can also exhibit outstanding dissolution characteristics even when a small amount of coating substance is used.