1,3,5-tribenzofuranyl-2,4,6-trimethylbenzene | 503631-17-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 2-芳基苯并呋喃类黄酮
• 英文名称: 1,3,5-tribenzofuranyl-2,4,6-trimethylbenzene
• 英文别名: 2-[3,5-Bis(1-benzofuran-2-yl)-2,4,6-trimethylphenyl]-1-benzofuran
• CAS: 503631-17-2
• 化学式: C₃₃H₂₄O₃
• 分子量: 468.552
• InChiKey: ISEYDJSJSQCHGG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.2
• 重原子数：
  36
• 可旋转键数：
  3
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  39.4
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Benzofuran compounds
  申请人：——

  公开号：US20030105343A1

  公开（公告）日：2003-06-05

  There is disclosed a method of preparing a branched benzofuran compound comprising a core moiety which contains at least one aromatic ring and which has at least three substituted or unsubstituted benzofuran groups covalently linked thereto. The method comprises the steps of (i) forming an intermediate ethynylene compound in which at least three benzene rings are each linked to the core moiety via an ethynylene bond, and where each benzene ring is substituted at the ortho position (relative to the position of the ethynylene bond) by a blocked carbonyloxy group, (ii) deblocking the carbonyloxy groups, and (iii) effecting ring closure by reaction between the deblocked carbonyloxy groups and the adjacent ethynylene bonds to form the furan rings of the benzofuran groups, whereby to produce the branched benzofuran compound.

  公开了一种制备支链苯并呋喃化合物的方法，其包含至少一个芳香环核心基团，且至少有三个取代或未取代的苯并呋喃基团与其共价键合。该方法包括以下步骤：(i)形成中间乙炔基化合物，在该化合物中，至少有三个苯环通过乙炔基键与核心基团连接，且每个苯环在邻位（相对于乙炔基键的位置）处被阻断的羰基氧基团取代，(ii)去除羰基氧基团，以及(iii)通过去除羰基氧基团和相邻乙炔基键之间的反应进行环闭合，形成苯并呋喃基团的呋喃环，从而产生支链苯并呋喃化合物。