1,1,1-Trifluor-2-trifluormethyl-4,4-dimethyl-pentan | 23157-74-6

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氟化物
• 英文名称: 1,1,1-Trifluor-2-trifluormethyl-4,4-dimethyl-pentan
• 英文别名: 1,1,1-trifluoro-4,4-dimethyl-2-trifluoromethyl-pentane；1,1,1-Trifluoro-4,4-dimethyl-2-(trifluoromethyl)pentane
• CAS: 23157-74-6
• 化学式: C₈H₁₂F₆
• 分子量: 222.174
• InChiKey: TYUBKQVYKBUBRQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  新戊烷 、 3,3-双(三氟甲基)-3H-双吖丙啶 反应 12.0h， 生成 1,1,1-Trifluor-2-trifluormethyl-4,4-dimethyl-pentan
  参考文献：
  名称：

  Anomalous reactions of bis(trifluoromethyl)diazomethane and bis(trifluoromethyl)diazirine with saturated hydrocarbons

  摘要：

  DOI：

  10.1021/ja01026a044

文献信息

• N-alkylation of acridans
  申请人：Siemens Healthcare Diagnostics Inc.

  公开号：US11203573B2

  公开（公告）日：2021-12-21

  The present invention provides compounds used in the synthesis of chemiluminescent acridinium compounds and methods of producing these compounds. Specifically, methods are provided for the N-alkylation of acridan compounds using alkylating reagents. Typically, these alkylating reagents comprise a protected sulfonate group protected with an acid-labile protecting group.

  本发明提供了用于合成化学发光吖啶化合物的化合物以及生产这些化合物的方法。具体而言，本发明提供了使用烷基化试剂对吖啶化合物进行 N-烷基化的方法。通常情况下，这些烷基化试剂包括一个受保护的磺酸基团和一个耐酸保护基团。
• ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES
  申请人：UNIVERSAL DISPLAY CORPORATION

  公开号：US20190252627A1

  公开（公告）日：2019-08-15

  A compound including a first ligand L A of Formula I is disclosed.
• AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS
  申请人：BRISTOL-MYERS SQUIBB COMPANY

  公开号：US20200347071A1

  公开（公告）日：2020-11-05

  The disclosure relates to compounds of formula I which are useful as kinase modulators including RIPK 1 modulation. The disclosure also provides methods of making and using the compounds for example in treatments related to necrosis or inflammation as well as other indications.
• N-ALKYLATION OF ACRIDANS
  申请人：Siemens Healthcare Diagnostics Inc.

  公开号：US20210230119A1

  公开（公告）日：2021-07-29

  The present invention provides compounds used in the synthesis of chemiluminescent acridinium compounds and methods of producing these compounds. Specifically, methods are provided for the N-alkylation of acridan compounds using alkylating reagents. Typically, these alkylating reagents comprise a protected sulfonate group protected with an acid-labile protecting group.