Atropasaeure-β-chlorethylester | 15895-96-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Atropasaeure-β-chlorethylester
• 英文别名: 2-Chloroethyl 2-phenylprop-2-enoate
• CAS: 15895-96-2
• 化学式: C₁₁H₁₁ClO₂
• 分子量: 210.66
• InChiKey: XGWXNANDRFPEFL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• COMPOSITE PARTICLE HAVING CARBODIIMIDE RESIN LAYER AND PROCESS FOR PRODUCING THE SAME
  申请人：Nisshinbo Industries, Inc.

  公开号：EP1528077A1

  公开（公告）日：2005-05-04

  A composite particle that can be easily converted to cured particle or half cured particle by the use of carbodiimide resin without changing of the configuration of matrix particle of, for example, a thermoplastic resin, excelling in mechanical and functional characteristics by virtue of the reaction capability inherently possessed by a carbodiimide group. In particular, a composite particle comprising matrix particle (A) having a functional group capable of reacting with a carbodiimide group and carbodiimide resin (B), characterized in that the functional group of the matrix particle (A) couples with the carbodiimide group of the carbodiimide resin (B) and that the composite particle is provided with an outer shell layer of carbodiimide resin (B) having an average thickness diameter (L), defined by the following formula [1], ranging from 0.01 to 20 µm : L = (L2 -L1) /2 [1] wherein L1 represents the average diameter of matrix particle, and L2 represents the average diameter of composite particle.

  一种复合微粒，通过使用碳化二亚胺树脂，可以在不改变热塑性树脂等基质微粒结构的情况下，轻松转化为固化微粒或半固化微粒，凭借碳化二亚胺基团固有的反应能力，具有优异的机械和功能特性。特别是一种复合颗粒，由基质颗粒（A）和碳化二亚胺树脂（B）组成，基质颗粒（A）具有能与碳化二亚胺基团反应的官能团，其特征在于基质颗粒（A）的官能团与碳化二亚胺树脂（B）的碳化二亚胺基团偶联，复合颗粒具有碳化二亚胺树脂（B）的外壳层，外壳层的平均厚度直径（L）由下式[1]定义，范围为 0.01 至 20 µm : L = (L2 -L1) /2 [1] 其中 L1 代表基质颗粒的平均直径，L2 代表复合颗粒的平均直径。
• FLAKY PARTICLES AND PROCESS FOR PRODUCTION THEREOF
  申请人：Nisshinbo Industries, Inc.

  公开号：EP1553124A1

  公开（公告）日：2005-07-13

  Flaky particles which are produced through easy conversion from mother particles by using an organic compound other than monomers having double bonds as the hardening and crosslinking agent and to which at least one mechanical or functional characteristic selected from among reactivity, close adhesion, and tackiness is imparted by the presence of part of the unreacted reactive groups of the organic compound inside and on the particles; and a process for the production of the flaky particles. More specifically, flaky particles composed of mother particles (A) having functional groups and an organic compound (B) which has groups reactive with the functional groups of the particles (A) and is soluble in a solvent, characterized in that at least part of the functional groups of the mother particles (A) and at least part of the reactive groups of the organic compound (B) react with each other to form crosslinks.

  片状颗粒，这种颗粒是通过使用具有双键的单体以外的有机化合物作为硬化剂和交联剂，从母颗粒中通过简易转化生产出来的，并且由于颗粒内部和颗粒上存在有机化合物的部分未反应的反应基团，使颗粒具有从反应性、紧密粘附性和粘性中选出的至少一种机械或功能特性；以及片状颗粒的生产工艺。更具体地说，片状颗粒由具有官能团的母颗粒（A）和具有与颗粒（A）的官能团反应的基团并可溶于溶剂的有机化合物（B）组成，其特征在于母颗粒（A）的至少部分官能团和有机化合物（B）的至少部分反应基团相互反应形成交联。
• Responsive microgel and methods related thereto
  申请人：——

  公开号：US20030152623A1

  公开（公告）日：2003-08-14

  A responsive microgel is provided which responds volumetrically and reversibly to a change in one or more aqueous conditions selected from the group consisting of (temperature, pH, and ionic conditions) comprised of an ionizable network of covalently cross-linked homopolymeric ionizable monomers wherein the ionizable network is covalently attached to an amphiphilic copolymer to form a plurality of ‘dangling chains’ and wherein the ‘dangling chains’ of amphiphilic copolymer form immobile micelle-like aggregates in aqueous solution. A responsive microgel is further provided that comprises at least one therapeutic entity and delivers a substantially linear and sustained release of the therapeutic entity under physiological conditions.

  本发明提供了一种响应型微凝胶，该微凝胶可对选自由温度、pH 值和离子条件组成的组中的一种或多种水性条件的变化作出体积上和可逆的响应、和离子条件）组成的共价交联均聚可离子化单体的可离子化网络，其中可离子化网络与两性共聚物共价连接，形成多条 "悬链"，两性共聚物的 "悬链 "在水溶液中形成不动的胶束状聚集体。还提供了一种响应性微凝胶，它包含至少一种治疗实体，并能在生理条件下提供治疗实体的线性和持续释放。
• Composite particle with a carbodimide resin layer and process for producing the same
  申请人：Hashiba Toshifumi

  公开号：US20050271875A1

  公开（公告）日：2005-12-08

  A composite particle that can be easily converted to cured particle or half cured particle by the use of carbodiimide resin without changing of the configuration of matrix particle of, for example. a thermoplastic resin, excelling in mechanical and functional characteristics by virtue of the reaction capability inherently possessed by a carbodiimide group. In particular, a composite particle comprising matrix particle (A) having a functional group capable of reacting with a carbodiimide group and carbodiimide resin (B), characterized in that the functional group of the matrix particle (A) couples with the carbodiimide group of the carbodiimide resin (B) and that the composite particle is provided with an outer shell layer of carbodiimide resin (B) having an average thickness diameter (L), defined by the following formula [1], ranging from 0.01 to 20 μm: L=(L 2 −L 1 )/2 [1] wherein L1 represents the average diameter of matrix particle, and L2 represents the average diameter of composite particle.

  一种复合粒子，它可以通过使用碳化二亚胺树脂，在不改变热塑性树脂等基质粒子的结构的情况下，轻松地转化为固化粒子或半固化粒子，凭借碳化二亚胺基团固有的反应能力，具有优异的机械和功能特性。特别是一种复合颗粒，由基质颗粒（A）和碳化二亚胺树脂（B）组成，基质颗粒（A）具有能与碳化二亚胺基团反应的官能团，其特征在于基质颗粒（A）的官能团与碳化二亚胺树脂（B）的碳化二亚胺基团偶联，复合颗粒具有碳化二亚胺树脂（B）的外壳层，外壳层的平均厚度直径（L）由下式[1]定义，范围为 0.01 至 20 μm：L=(L 2 -L 1 ) /2 [1] 其中 L1 代表基质颗粒的平均直径，L2 代表复合颗粒的平均直径。
• Flat particles and process for production thereof
  申请人：Hashiba Toshifumi

  公开号：US20060052549A1

  公开（公告）日：2006-03-09

  Flaky particles which are produced through easy conversion from mother particles by using an organic compound other than monomers having double bonds as the hardening and crosslinking agent and to which at least one mechanical or functional characteristic selected from among reactivity, close adhesion, and tackiness is imparted by the presence of part of the unreacted reactive groups of the organic compound inside and on the particles; and a process for the production of the flaky particles. More specifically, flaky particles composed of mother particles (A) having functional groups and an organic compound (B) which has groups reactive with the functional groups of the particles (A) and is soluble in a solvent, characterized in that at least part of the functional groups of the mother particles (A) and at least part of the reactive groups of the organic compound (B) react with each other to form crosslinks.

  片状颗粒，它是通过使用除具有双键的单体以外的有机化合物作为硬化和交联剂，从母颗粒中通过简易转化生产出来的，并且由于有机化合物的部分未反应的反应基团存在于颗粒内部和颗粒上，赋予了颗粒至少一种机械或功能特性，这些特性可从反应性、紧密粘附性和粘性中选择；以及片状颗粒的生产工艺。更具体地说，片状颗粒由具有官能团的母颗粒（A）和具有与颗粒（A）的官能团反应的基团并可溶于溶剂的有机化合物（B）组成，其特征在于母颗粒（A）的至少部分官能团和有机化合物（B）的至少部分反应基团相互反应形成交联。