[(nBu)(nHex)Sn{N-hydroxybenzamide}2] | 1428738-10-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [(nBu)(nHex)Sn{N-hydroxybenzamide}2]
• 英文别名: [(ⁿBu)(ⁿHex)Sn{N-hydroxybenzamide}₂]
• CAS: 1428738-10-6
• 化学式: C₂₄H₃₄N₂O₄Sn
• 分子量: 533.255
• InChiKey: AOSVABLVILHJCN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  butyldichloro(hexyl)stannane 在 氨 作用下， 以 乙醇 、 甲苯 为溶剂， 反应 6.0h， 生成 [(nBu)(nHex)Sn{N-hydroxybenzamide}2]
  参考文献：
  名称：

  Synthesis, characterization and cytotoxicity of novel mixed-ligand butyl-hexyltin(IV) complexes with N-hydroxybenzamides

  摘要：

  Five new mononuclear butyl-hexyltin(IV) complexes with para-position substituents of N-hydroxybenzamide anions [para-position substituent = H (1), F (2), Cl (3), Br (4), 1(5)], formulated as the [(n)Bu(n)Hex-SnL2] (Bu = butyl, Hex = hexyl, HL = substituted N-hydroxybenzamide), were prepared and characterized by elemental analyses, FT-IR, H-1, C-13, Sn-119 NMR spectroscopies. Crystal structure of complex 2 was determined by X-ray diffraction analysis. The cytotoxicity was tested by SRB assay. The results indicate that the complex 5 with iodine atoms has the best cytotoxicity against KB cells, even being better than that of cisplatin. It suggests that both halogens and alkyl groups around tin have important effects on cytotoxicity. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2012.08.055