2-tert-Butylsulfanyl-3-nitro-pyridine | 84358-80-5

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 2-tert-Butylsulfanyl-3-nitro-pyridine
• 英文别名: Uddxhsyniqarci-uhfffaoysa-；2-tert-butylsulfanyl-3-nitropyridine
• CAS: 84358-80-5
• 化学式: C₉H₁₂N₂O₂S
• 分子量: 212.272
• InChiKey: UDDXHSYNIQARCI-UHFFFAOYSA-N

物化性质

• 熔点：
  33-34 °C
• 沸点：
  309.7±27.0 °C(Predicted)
• 密度：
  1.21±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  84
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2-甲基-2-丙硫醇钠盐 、 2-氯-3-硝基吡啶 以32%的产率得到
  参考文献：
  名称：

  BECHER, J.;LUNDSGAARD, J., PHOSPH. AND SULFUR, 1983, 14, N 2, 131-138

  摘要：

  DOI：

文献信息

• Becher, Jan; Lundsgaard, John, Phosphorus and Sulfur and the Related Elements, 1982, vol. 14, p. 131 - 138
  作者：Becher, Jan、Lundsgaard, John

  DOI：——

  日期：——
• Homogeneous Erythropoietin and Other Peptides and Proteins, Methods and Intermediates for Their Preparation
  申请人：Danishefsky Samuel J.

  公开号：US20100081786A1

  公开（公告）日：2010-04-01

  The present invention provides isolated homogeneous polyfunctionalized proteins (e.g., erythropoietin), isolated glycopeptides, and a method for preparing polyfunctionalized peptides and/or proteins via cysteine-free native chemical ligation. In certain embodiments, the invention provides an isolated homogeneous polyfunctionalized protein having the structure (I). In certain other embodiments, the invention provides an isolated glycopeptide having Formula (II). In certain other embodiments, the inventive method is a method for preparing a polyfunctionalized peptide comprising a peptidic backbone made up of four or more amino acids, wherein two or more non-adjacent amino acids are independently substituted with a moiety having the structure (III)-LH. wherein A and L1 are as defined herein.
• ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, AND, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM AND PATTERN FORMING METHOD, EACH USING THE SAME
  申请人：FUJIFILM Corporation

  公开号：US20140295332A1

  公开（公告）日：2014-10-02

  An actinic ray-sensitive or radiation-sensitive resin composition, which is excellent in sensitivity, resolution, a pattern profile and a depth of focus (DOF), and, an actinic ray-sensitive or radiation-sensitive film and a pattern forming method, each using the same, are provided. The actinic ray-sensitive or radiation-sensitive resin composition includes a nitrogen-containing compound and a resin (Ab) capable of varying a polarity or an alkali solubility thereof by the action of an acid.
• HINDERED DISULFIDE DRUG CONJUGATES
  申请人：Genentech, Inc.

  公开号：US20170112891A1

  公开（公告）日：2017-04-27

  The invention relates generally to disulfide drug conjugates wherein a linker comprising a sulfur-bearing carbon atom substituted with at least one hydrocarbyl or substituted hydrocarbyl is conjugated by a disulfide bond to a cysteine sulfur atom of a targeting carrier, and wherein the linker is further conjugated to a drug moiety. The invention further relates to activated linker-drug conjugates suitable for conjugation to a targeting carrier by a disulfide bond. The invention further relates to methods for preparing hindered disulfide drug conjugates.
• US8754192B2
  申请人：——

  公开号：US8754192B2

  公开（公告）日：2014-06-17

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