3,3'-Diamino-2,2'-dipyridyl-sulfid | 4869-24-3

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 3,3'-Diamino-2,2'-dipyridyl-sulfid
• 英文别名: 2,2'-sulfanediyl-bis-pyridin-3-ylamine；2-(3-Aminopyridin-2-yl)sulfanylpyridin-3-amine
• CAS: 4869-24-3
• 化学式: C₁₀H₁₀N₄S
• 分子量: 218.282
• InChiKey: WLRKBOINQIHJQC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  103
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• p-(sulfonyl) aryl and heteroarylamines as anti-inflammatory agents
  申请人：——

  公开号：US20020052349A1

  公开（公告）日：2002-05-02

  This invention relates to anti-inflammatory and analgesic compounds, especially to certain p-(sulfonyl)phenyl amino derivatives, pharmaceutical compositions containing them, methods for their use, and methods for preparing these compounds.

  这项发明涉及抗炎和镇痛化合物，特别是某些p-(磺酰基)苯基氨基衍生物，包含它们的药物组合物，它们的使用方法以及制备这些化合物的方法。
• P-(sulfonyl) aryl and heteroarylamines-as anti-inflammatory agents
  申请人：Krauss Elisabeth Nancy

  公开号：US20060173075A1

  公开（公告）日：2006-08-03

  This invention relates to anti-inflammatory and analgesic compounds, especially to certain p-(sulfonyl)phenyl amino derivatives, pharmaceutical compositions containing them, methods for their use, and methods for preparing these compounds.

  本发明涉及抗炎和镇痛化合物，特别是某些p-(磺酰基)苯基氨基衍生物，包含它们的制药组合物，使用它们的方法以及制备这些化合物的方法。
• P-(SULFONYL)-ARYL AND -HETEROARYL AMINES
  申请人：F. HOFFMANN-LA ROCHE AG

  公开号：EP1278723A2

  公开（公告）日：2003-01-29
• US7071177B2
  申请人：——

  公开号：US7071177B2

  公开（公告）日：2006-07-04
• [EN] P-(SULFONYL)ARYL AND HETEROARYLS<br/>[FR] P-(SULFONYL)ARYLE ET HETEROARYLES
  申请人：HOFFMANN LA ROCHE

  公开号：WO2001083434A2

  公开（公告）日：2001-11-08

  This invention relates to anti-inflammatory and analgesic compounds, especially to certain p-(sulfonyl)phenyl amino derivatives, pharmaceutical compositions containing them, methods for their use, and methods for preparing these compounds. The claimed compounds have prostaglandin G/H synthase inhibitor activity and are suitable for the treatment of inflammatory diseases, such as myositis, synovitis, rheumatoid arthritis, osteoarthritis, gout, ankylosing spondylitis and bursitis, for the treatment of Alzheimer's disease or of an autoimmune disease such as systemic lupus erythematosus and type I diabetes.