AHN 1-055 hydrochloride;AHN 1-055 hydrochloride;AHN 1055 hydrochloride

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: AHN 1-055 hydrochloride;AHN 1-055 hydrochloride;AHN 1055 hydrochloride
• 英文别名: 3-[bis(4-fluorophenyl)methoxy]-8-methyl-8-azabicyclo[3.2.1]octane;hydrochloride
• 化学式: C21H24ClF2NO
• 分子量: 379.9
• InChiKey: YOORVSGDAHWVMC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.12
• 重原子数：
  26
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  12.5
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• [EN] GHB TREATMENT METHODS<br/>[FR] METHODES DE TRAITEMENT DE TROUBLES LIES AU GHB
  申请人：BAYLOR RES INST

  公开号：WO2004041207A2

  公开（公告）日：2004-05-21

  Treatment methods for GHB toxicity and overdose are disclosed wherein the deleterious effects of GHB are blocked by either postponing the removal of dopamine in the synaptic cleft or improving the dopaiminergic function therein. These methods are effective for treating or preventing GHB toxicity due to SSADH deficiency disease, accidental GHB toxicity and overdose in therapeutic administration for treatment of narcolepsy and alcohol/opiate-withdrawal syndromes, and GHB toxicity or overdose due to inappropriate recreational use.