N-methyl-1-[1-(4-chlorophenyl)cyclobutyl]butylamine hydrochloride | 84467-80-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-methyl-1-[1-(4-chlorophenyl)cyclobutyl]butylamine hydrochloride
• 英文别名: 1-[1-(4-chlorophenyl)cyclobutyl]-N-methylbutan-1-amine;hydrochloride
• CAS: 84467-80-1
• 化学式: C₁₅H₂₂ClN*ClH
• 分子量: 288.26
• InChiKey: VZIZWMVFDMWVKA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.57
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  12
• 氢给体数：
  2
• 氢受体数：
  1

文献信息

• N-halothiosulfonamide modified rubber products and process for preparing the same
  申请人：EXXON CHEMICAL PATENTS INC.

  公开号：EP0430529A2

  公开（公告）日：1991-06-05

  N-halothiosulfonamide-modified rubber products are provided. The modified rubber products are prepared by reaction of a rubber, such as a butyl rubber or a halogenated butyl rubber, with a N-halothiosulfonamide in the absence or in the presence of a catalyst.

  提供了 N-卤代硫磺酰胺改性橡胶制品。改性橡胶制品是通过橡胶（如丁基橡胶或卤化丁基橡胶）在无催化剂或有催化剂的情况下与 N-卤代硫磺酰胺反应制备的。
• N-halothiosulfonamide-modified non-rubbery thermoplastic polyolefins
  申请人：EXXON CHEMICAL PATENTS INC.

  公开号：EP0431788A2

  公开（公告）日：1991-06-12

  N-halothiosulfonamide-modified non-rubbery thermoplastic polyolefins are provided. The modified polyolefin products are prepared by reaction of a non-­rubbery thermoplastic polyolefin polymer with an N-halothiosulfonamide in the absence or, preferably, in the presence of a catalyst. The preferred catalyst for use in the preparation of these products are salts of weak acids of specified metals.

  提供了 N-卤代硫磺酰胺改性非橡胶热塑性聚烯烃。改性聚烯烃产品是在无催化剂或有催化剂的情况下，通过非橡胶热塑性聚烯烃聚合物与 N-卤代硫磺酰胺反应制备的。用于制备这些产品的催化剂最好是特定金属的弱酸盐。
• Process for preparation of N-halothiosulfonamide modified terpolymers
  申请人：THE GOODYEAR TIRE & RUBBER COMPANY

  公开号：EP0733651A1

  公开（公告）日：1996-09-25

  The subject invention discloses a process for preparing an N-chloro(or bromo)thio-sulfonamide-modified terpolymer which comprises reacting: (a) a terpolymer of ethylene, an α-olefin containing from 3-16 carbon atoms, and 5-ethylidene-2-norbornene, with (b) an N-chloro(or bromo)thio-sulfonamide of the formula: wherein R1 and R2 are selected from the group consisting of alkyl radicals having 1 to 20 carbon atoms, aralkyl radicals having 7 to 20 carbon atoms and aryl and substituted aryl radical having 6 to 10 carbon atoms and wherein R1 is also selected from radicals having the formula: wherein R3 and R4 are individually selected from said alkyl, aralkyl, aryl and substituted aryl radicals and wherein R3 and R4 can be joined together to represent radicals selected from (̵CH2)̵n, where n is an integer of 4 to 7, and (̵CH2)̵20(̵CH2)̵2, and wherein X is selected from chlorine and bromine; in the presence of at least a stoichiometric amount of a hydrohalic acid acceptor.

  本发明公开了一种制备 N-氯（或溴）硫磺酰胺改性三元共聚物的工艺，该工艺包括使以下物质发生反应： (a) 乙烯、含有 3-16 个碳原子的 α 烯烃和 5-亚乙基-2-降冰片烯的三元共聚物，与 (b) 式中的 N-氯（或溴）硫代磺酰胺： 其中 R1 和 R2 选自具有 1 至 20 个碳原子的烷基、具有 7 至 20 个碳原子的芳基和具有 6 至 10 个碳原子的芳基和取代芳基组成的组，其中 R1 还选自具有以下式子的基团： 其中 R3 和 R4 单独选自所述烷基、烷基、芳基和取代芳基，且 R3 和 R4 可连接在一起以代表选自 (̵CH2)̵n 的基，其中 n 为 4 至 7 的整数，和 (̵ )̵20(̵ )̵2 的基，且 X 选自氯和溴，在至少有一定量的氢卤酸受体存在的情况下。
• N-halothio-amide-modified elastomers and their application as adhesives for precured elastomeric substrates
  申请人：THE GOODYEAR TIRE & RUBBER COMPANY

  公开号：EP0989171A1

  公开（公告）日：2000-03-29

  New modified elastomers, prepared by reaction of polydiene elastomers with N-halothio-sulfonamides or N-halothio-carboxamides are disclosed. The modified elastomers, diluted with solvents or oils, are applied as an adhesive layer between the surfaces of sulfur-vulcanized elastomeric components and vulcanized to produce an adhesive bond. The process is useful for adhering precured tire treads to cured tire carcasses and is thus applicable in the manufacture of retreaded tires. This invention more specifically discloses an adhesive composition which is comprised of a mixture of a rubbery polymer selected from the group consisting of N-halothio-sulfonamide-modified rubbery polymers and N-halothio-carboxamide-modified rubbery polymers in an oil. The present invention further discloses a laminated rubber article which is comprised of a first rubber layer and a second rubber layer wherein the first rubber layer is adhered to the second rubber layer with a rubbery polymer selected from the group consisting of N-halothio-sulfonamide-modified rubbery polymers and N-halothio-carboxamide-modified rubbery polymers.

  本发明公开了通过聚二烯弹性体与 N-卤代磺酰胺或 N-卤代羧酰胺反应制备的新型改性弹性体。改性弹性体用溶剂或油稀释后，作为粘合层涂在硫磺硫化弹性体部件的表面之间，并经硫化产生粘合剂。该工艺可用于将预硫化轮胎胎面粘附到硫化轮胎胎体上，因此适用于制造翻新轮胎。本发明更具体地公开了一种粘合剂组合物，它由选自 N-卤代磺酰胺改性橡胶聚合物和 N-卤代甲酰胺改性橡胶聚合物的橡胶聚合物在油中的混合物组成。本发明进一步公开了一种层压橡胶制品，它由第一橡胶层和第二橡胶层组成，其中第一橡胶层用选自 N-卤代磺酰胺改性橡胶聚合物和 N-卤代甲酰胺改性橡胶聚合物的橡胶聚合物粘附在第二橡胶层上。
• SEROTONIN-NOREPINEPHRINE REUPTAKE INHIBITORS (SNRIs) AND SIGMA RECEPTOR LIGANDS COMBINATIONS
  申请人：Laboratorios del Dr. Esteve, S.A.

  公开号：EP3082782A1

  公开（公告）日：2016-10-26