sodium 1-amino-4-((3-(tert-butyl)phenyl)amino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate | 1363419-32-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: sodium 1-amino-4-((3-(tert-butyl)phenyl)amino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
• 英文别名: Sodium;1-amino-4-(3-tert-butylanilino)-9,10-dioxoanthracene-2-sulfonate
• CAS: 1363419-32-2
• 化学式: C₂₄H₂₁N₂O₅S*Na
• 分子量: 472.497
• InChiKey: MCJZHLYTYCHCLM-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  0.99
• 重原子数：
  33
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  138
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• Anthraquinone Compounds and Their Uses
  申请人：McHale Noel

  公开号：US20130296588A1

  公开（公告）日：2013-11-07

  The present invention relates to a compound comprising a substituted or unsubstituted anthraquinone, or a salt or isomer thereof, for use in treating a disorder caused by or associated with dysfunctional ion channel activity. The invention finds utility in the treatment of disorders associated with smooth muscle tone and contraction, such as partial hypertension; myocardial infarction; faecal incontinence; constipation; gastro oesophageal reflux; impaired gastrointenstinal passage; urinary incontinence; erectile dysfunction; and asthma.
• ANTHRAQUINONE COMPOUNDS AND THEIR USES
  申请人：DUNDALK INSTITUTE OF TECHNOLOGY

  公开号：US20160243066A1

  公开（公告）日：2016-08-25

  The present invention relates to a compound comprising a substituted or unsubstituted anthraquinone, or a salt or isomer thereof, for use in treating a disorder caused by or associated with dysfunctional ion channel activity. The invention finds utility in the treatment of disorders associated with smooth muscle tone and contraction, such as but not limited to partial hypertension; myocardial infarction; faecal incontinence; constipation; gastro oesophageal reflux; impaired gastrointestinal passage; urinary incontinence; erectile dysfunction; and asthma.
• US9877940B2
  申请人：——

  公开号：US9877940B2

  公开（公告）日：2018-01-30