3-Sulfanylbenzoyl chloride | 70074-41-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-Sulfanylbenzoyl chloride
• CAS: 70074-41-8
• 化学式: C₇H₅ClOS
• 分子量: 172.63
• InChiKey: NDJYILWWNRCFKX-UHFFFAOYSA-N

物化性质

• 沸点：
  262.7±23.0 °C(Predicted)
• 密度：
  1.343±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  18.1
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Tetrazolones as a carboxylic acid bioisosteres
  申请人：Rigel Pharmaceuticals, Inc.

  公开号：US10450280B2

  公开（公告）日：2019-10-22

  The present disclosure provides compounds that include a tetrazolone derivative of a carboxyl group of an active agent. This disclosure also relates to pharmaceutical compositions that include these compounds, methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.

  本公开提供了包括活性剂羧基四唑酮衍生物的化合物。本公开还涉及包括这些化合物的药物组合物、使用这些化合物治疗各种疾病和失调的方法以及制备这些化合物的工艺。
• Tetrazolones as a Carboxylic Acid Bioisosteres
  申请人：RIGEL PHARMACEUTICALS, INC.

  公开号：US20170129862A1

  公开（公告）日：2017-05-11

  The present disclosure provides compounds that include a tetrazolone derivative of a carboxyl group of an active agent. This disclosure also relates to pharmaceutical compositions that include these compounds, methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.
• US4112219A
  申请人：——

  公开号：US4112219A

  公开（公告）日：1978-09-05
• US9701647B2
  申请人：——

  公开号：US9701647B2

  公开（公告）日：2017-07-11