N-[2]pyridyl-stearamide | 760214-97-9

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-[2]pyridyl-stearamide
• 英文别名: N-[2]Pyridyl-stearamid；N-pyridin-2-yloctadecanamide
• CAS: 760214-97-9
• 化学式: C₂₃H₄₀N₂O
• 分子量: 360.583
• InChiKey: VMSQIINLYSSBFV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9
• 重原子数：
  26
• 可旋转键数：
  17
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.74
• 拓扑面积：
  42
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N-[2]pyridyl-stearamide 、 2-溴苯乙酮 以 乙酸乙酯 为溶剂， 反应 3.0h， 生成 2-octadecanoylamino-1-(2-oxo-2-phenylethyl)pyridinium bromide
  参考文献：
  名称：

  N-Phenacylpyridinium Bromides as Acid Corrosion Inhibitors

  摘要：

  The inhibiting effect of N-phenacylpyridinium bromides with the amide group in the pyridine ring on corrosion of carbon steel in 3 M sulfuric acid is studied. A relationship between the nature of substituents at the amide group and the corrosion-protective properties of the compounds studied is revealed. Compounds demonstrating high protection efficiency in acid solutions at elevated temperatures are found.

  DOI：

  10.1023/b:rjac.0000044159.65275.47
• 作为产物：
  描述：

  硬脂酸 在 氯化亚砜 、 三乙胺 作用下， 以 苯 为溶剂， 反应 3.0h， 生成 N-[2]pyridyl-stearamide
  参考文献：
  名称：

  N-Phenacylpyridinium Bromides as Acid Corrosion Inhibitors

  摘要：

  The inhibiting effect of N-phenacylpyridinium bromides with the amide group in the pyridine ring on corrosion of carbon steel in 3 M sulfuric acid is studied. A relationship between the nature of substituents at the amide group and the corrosion-protective properties of the compounds studied is revealed. Compounds demonstrating high protection efficiency in acid solutions at elevated temperatures are found.

  DOI：

  10.1023/b:rjac.0000044159.65275.47

文献信息

• Takase, Nippon Kagaku Zasshi, 1953, vol. 74, p. 59,60
  作者：Takase

  DOI：——

  日期：——
• Zetzsche et al., Chemische Berichte, 1938, vol. 71, p. 1516,1518
  作者：Zetzsche et al.

  DOI：——

  日期：——
• A METHOD FOR TREATING PERIPHERAL INFLAMMATORY DISEASE
  申请人：Dublin City University

  公开号：EP3297621A1

  公开（公告）日：2018-03-28
• [EN] A METHOD FOR TREATING PERIPHERAL INFLAMMATORY DISEASE<br/>[FR] PROCÉDÉ DE TRAITEMENT D'UNE MALADIE INFLAMMATOIRE PÉRIPHÉRIQUE
  申请人：UNIV DUBLIN CITY

  公开号：WO2016185025A1

  公开（公告）日：2016-11-24

  An active for use in the treatment or inhibition of an inflammatory disease associated with over- activation of Toll-like Receptor 4 (TLR4), Toll-like Receptor 2 (TLR2) and Myeloid differentiating protein 88 (Myd88) adaptor-like protein (Ma1) while maintaining a subject's ability to respond normally to a pathogen, in which the active is an oleamide or an immunomodulatory analogue thereof.