(+/-)-N-{4-[2-(2,5-dioxo-4,4-diphenyl-imidazolidin-1-yl)-acetyl]phenyl}-2-(4-isobutyl-phenyl)-propionamide | 1141888-14-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: (+/-)-N-{4-[2-(2,5-dioxo-4,4-diphenyl-imidazolidin-1-yl)-acetyl]phenyl}-2-(4-isobutyl-phenyl)-propionamide
• 英文别名: N-[4-[2-(2,5-dioxo-4,4-diphenylimidazolidin-1-yl)acetyl]phenyl]-2-[4-(2-methylpropyl)phenyl]propanamide
• CAS: 1141888-14-3
• 化学式: C₃₆H₃₅N₃O₄
• 分子量: 573.692
• InChiKey: IJXKFJCXDAJGOC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  43
• 可旋转键数：
  10
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  95.6
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• ORGANIC COMPOUNDS
  申请人：Nozulak Joachim

  公开号：US20090099243A1

  公开（公告）日：2009-04-16

  The invention relates to compound of the formula (I) in which the substituents are as defined in the specification; in free base form or in acid addition salt form; to its preparation, to its use as medicament and to medicaments comprising it.

  本发明涉及式(I)的化合物，其中取代基如规范中所定义；以自由碱或酸盐形式存在；其制备方法，以及其作为药物的用途和包含它的药物。
• IMIDAZOLIDINE-2,4-DIONE (HYDANTOIN) DERIVATIVES USEFUL AS NPY Y2 RECEPTOR MODULATORS
  申请人：Novartis AG

  公开号：EP2212314A1

  公开（公告）日：2010-08-04
• [EN] IMIDAZOLIDINE-2,4-DIONE (HYDANTOIN) DERIVATIVES USEFUL AS NPY Y2 RECEPTOR MODULATORS<br/>[FR] DÉRIVÉS D'IMIDAZOLIDINE-2,4-DIONE (HYDANTOÏNE) UTILES COMME MODULATEURS DU RÉCEPTEUR Y2 DU NPY
  申请人：NOVARTIS AG

  公开号：WO2009050200A1

  公开（公告）日：2009-04-23

  The invention relates to compound of the formula (I) in which the substituents are as defined in the specification; in free base form or in acid addition salt form; to its preparation, to its use as medicament and to medicaments comprising it.