N-(3-amino-1H-indazol-5-yl)-2-(3-hydroxyphenyl)acetamide | 871792-36-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(3-amino-1H-indazol-5-yl)-2-(3-hydroxyphenyl)acetamide
• CAS: 871792-36-8
• 化学式: C₁₅H₁₄N₄O₂
• 分子量: 282.302
• InChiKey: NHSVDLPSBJFDQN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  104
• 氢给体数：
  4
• 氢受体数：
  4

文献信息

• 3-Aminoindazoles
  申请人：Dorsch Dieter

  公开号：US20070232620A1

  公开（公告）日：2007-10-04

  Novel 3-aminoindazoles of the formula (I) are SGK inhibitors and can be used for the treatment of SGK-induced diseases and conditions, such as diabetes, obesity, metabolic syndrome (dyslipidaemia), systemic and pulmonary hypertonia, cardiovascular diseases and renal diseases, generally in fibrosis and inflammatory processes of any type.

  公式（I）的新型3-氨基吲唑是SGK抑制剂，可用于治疗由SGK引起的疾病和症状，如糖尿病、肥胖症、代谢综合征（脂质代谢紊乱）、全身和肺动脉高压、心血管疾病和肾脏疾病，通常用于任何类型的纤维化和炎症过程。
• 3-AMINOINDAZOLE DERIVATE UND IHRE VERWENDUNG ZUR BEHANDLUNG SGK-BEDINGTEN KRANKHEITEN
  申请人：Merck Patent GmbH

  公开号：EP1765788A2

  公开（公告）日：2007-03-28
• Reactive Dye and Process of Printing Same
  申请人：Xu Ming

  公开号：US20090021568A1

  公开（公告）日：2009-01-22

  A method of printing an ink that comprises reactive dyes as colorants. The ink has at least one cyclodextrin (CD) compound to react with reactive dye molecules, while a hydrophobic cavity is filled with a disperse dye component to create an encapsulation prior to the ink formulation stage. The ink also includes a crosslinking agent that is capable of creating a chemical bonding reaction between the unreacted portion of the hydroxyl functional groups of cyclodextrin (CD), an optional alkaline substance, and other optional ink additives. Permanently bonded color images are provided by the reaction between the chemically altered and colored cyclodextrin (CD) and the final substrate, which may be any cellulosic, protein, or polyamide fiber material, or mixtures with polyester, by the application of energy.
• US7527655B1
  申请人：——

  公开号：US7527655B1

  公开（公告）日：2009-05-05
• US7872039B2
  申请人：——

  公开号：US7872039B2

  公开（公告）日：2011-01-18