Dinitroporphin | 52358-26-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四吡咯及其衍生物
• 英文名称: Dinitroporphin
• 英文别名: 5,10-dinitro-porphyrin
• CAS: 52358-26-6
• 化学式: C₂₀H₁₂N₆O₄
• 分子量: 400.353
• InChiKey: MPVZQRKNYOVLNL-UPVVYHLRSA-N

文献信息

• Carboranylporphyrins and uses thereof
  申请人：Miura Michiko

  公开号：US20080131376A1

  公开（公告）日：2008-06-05

  The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity carborane-containing porphyrin compounds with halide, amine, or nitro groups and methods for their use particularly in boron neutron capture therapy (BNCT), X-ray radiation therapy (XRT), and photodynamic therapy (PDT) for the treatment of tumors of the brain, head and neck, and surrounding tissue. The invention is also directed to using these carborane-containing porphyrin compounds in methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET.

  本发明涉及低毒性硼化合物及其在肿瘤治疗、可视化和诊断中的使用方法。更具体地说，本发明涉及含有卤素、胺基或硝基的低毒性卡博烷基卟啉化合物及其在硼中子俘获治疗（BNCT）、X射线放疗（XRT）和光动力疗法（PDT）中的使用方法，用于治疗脑部、头颈部和周围组织的肿瘤。本发明还涉及使用这些卡博烷基卟啉化合物的方法进行肿瘤成像和/或诊断，如MRI、SPECT或PET。
• Carbonylporphyrins and Uses Thereof
  申请人：Miura Michiko

  公开号：US20130004419A1

  公开（公告）日：2013-01-03

  The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity carborane-containing porphyrin compounds with halide, amine, or nitro groups and methods for their use particularly in boron neutron capture therapy (BNCT), X-ray radiation therapy (XRT), and photodynamic therapy (PDT) for the treatment of tumors of the brain, head and neck, and surrounding tissue. The invention is also directed to using these carborane-containing porphyrin compounds in methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET.

  本发明涉及低毒性硼化合物及其在肿瘤治疗、可视化和诊断中的应用方法。更具体地，本发明涉及含有卤素、胺基或硝基的低毒性碳硼烷卟啉化合物及其在硼中子俘获治疗（BNCT）、X射线放疗（XRT）和光动力疗法（PDT）中的应用方法，用于治疗脑、头颈以及周围组织的肿瘤。本发明还涉及使用这些碳硼烷卟啉化合物进行肿瘤成像和/或诊断的方法，例如MRI、SPECT或PET。
• Nitrated metalloporphyrins as catalysts for alkane oxidation
  申请人：SUN COMPANY, INC. (R&M)

  公开号：EP0532326A2

  公开（公告）日：1993-03-17

  In one embodiment, alkanes are oxidized by contact with oxygen-containing gas in the presence as catalyst of a metalloporphyrin in which hydrogen atoms in the porphyrin ring have been replaced with one or more nitro groups. Hydrogen atoms in the porphyrin may also be substituted with halogen atoms. In another embodiment, new compositions of matter comprise nitro-substituted metal complexes of porphyrins are catalysts for the oxidation of alkanes. The metal is iron, chromium, manganese, ruthenium, copper or cobalt. The porphyrin ring has nitro groups attached thereto in meso and/or β-pyrrolic positions.

  在一个实施方案中，在金属卟啉作为催化剂存在的情况下，通过与含氧气体接触氧化烷烃，金属卟啉环中的氢原子被一个或多个硝基取代。卟啉中的氢原子也可以被卤素原子取代。在另一个实施方案中，由卟啉的硝基取代金属络合物组成的新物质组合物是烷烃氧化的催化剂。金属是铁、铬、锰、钌、铜或钴。卟啉环的中位和/或β-吡咯位上连接有硝基。
• CARBORANYLPORPHYRINS AND USES THEREOF
  申请人：Brookhaven Sciences Associates, LLC

  公开号：EP2099304A2

  公开（公告）日：2009-09-16
• US4908442A
  申请人：——

  公开号：US4908442A

  公开（公告）日：1990-03-13