N-butyl-N-(2'-benzo[b]thienyl)-3-aminobenzo[b]thiophene | 1174151-89-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-butyl-N-(2'-benzo[b]thienyl)-3-aminobenzo[b]thiophene
• 英文别名: N-(1-benzothiophen-3-yl)-N-butyl-1-benzothiophen-2-amine
• CAS: 1174151-89-3
• 化学式: C₂₀H₁₉NS₂
• 分子量: 337.51
• InChiKey: JTICSGOFBLUHCG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.2
• 重原子数：
  23
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  59.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N-butyl-N-(2'-benzo[b]thienyl)-3-aminobenzo[b]thiophene 在 正丁基锂 、 copper dichloride 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 反应 8.0h， 以20%的产率得到N-butyl-dibenzothieno[2,3-b: 2',3'-d]pyrrole
  参考文献：
  名称：

  Synthesis and Properties of Symmetric and Unsymmetric Dibenzothienopyrroles

  摘要：

  Symmetrical and unsymmetrical heteroacenes containing thiophene and pyrrole rings were synthesized. The unsymmetrical heteroacene was synthesized In two steps involving an unexpected palladium catalyzed amination of alkyl or aryl amines with benzo[b]thiophene followed by a copper catalyzed coupling. The symmetrical heteroacene was obtained by a palladium catalyzed amination reaction and also by a copper catalyzed amidation reaction. The crystal structure, photophysical and electrochemical properties of symmetrical and unsymmetrical heteroacenes are described.

  DOI：

  10.1021/ol901133m
• 作为产物：
  描述：

  3-溴苯并噻吩 、 正丁胺 在 palladium diacetate 、 sodium t-butanolate 、 tri tert-butylphosphoniumtetrafluoroborate 作用下， 以 甲苯 为溶剂， 反应 5.0h， 以40%的产率得到N-butyl-N-(2'-benzo[b]thienyl)-3-aminobenzo[b]thiophene
  参考文献：
  名称：

  Synthesis and Properties of Symmetric and Unsymmetric Dibenzothienopyrroles

  摘要：

  Symmetrical and unsymmetrical heteroacenes containing thiophene and pyrrole rings were synthesized. The unsymmetrical heteroacene was synthesized In two steps involving an unexpected palladium catalyzed amination of alkyl or aryl amines with benzo[b]thiophene followed by a copper catalyzed coupling. The symmetrical heteroacene was obtained by a palladium catalyzed amination reaction and also by a copper catalyzed amidation reaction. The crystal structure, photophysical and electrochemical properties of symmetrical and unsymmetrical heteroacenes are described.

  DOI：

  10.1021/ol901133m