[Pt(II)(N,N'-bis(2-pyridyl)thiourea)2] | 1314132-17-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: [Pt(II)(N,N'-bis(2-pyridyl)thiourea)2]
• CAS: 1314132-17-6
• 化学式: C₂₂H₁₈N₈PtS₂
• 分子量: 653.651
• InChiKey: ULAUBYWWOLYTJZ-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  potassium tetrachloroplatinate(II) 、 1,3-二(吡啶-2-基)硫脲 以 乙醇 为溶剂， 生成 [Pt(II)(N,N'-bis(2-pyridyl)thiourea)2]
  参考文献：
  名称：

  Pt(II), Pd(II) and UO2(II) complexes of N,N′-bis(2-pyridyl)thiourea; structural, thermal and biological studies

  摘要：

  Novel complexes of Pt2+, Pd2+ and UO22+ with N,N'-bis(2-pyridyl)thiourea (H2BPT) 1 were synthesized. These complexes namely [Pt(HBPT)(2)] 2, [Pd(HBPT)(2)] 3 and [UO2(HBPT)(OAc)(H2O)] 4, were characterized by elemental analysis and spectral measurements. Suggested structures (square-planar for both 2 and 3 complexes and pentagonal-bipyramidal geometry for 4) were confirmed by applying geometry optimization and conformational analysis.Thermal properties and decomposition kinetics of all compounds are investigated. The interpretation, mathematical analysis and evaluation of kinetic parameters (E, A, Delta H, Delta S and Delta G) of all thermal decomposition stages have been evaluated using Coats-Redfern, Horowitz-Metzger and MKN methods. The biochemical studies showed that, complex 2 has powerful and complete degradation effect on DNA. The antibacterial screening demonstrated that, complex 2 has the maximum and broad range activities against Gram-positive and Gram-negative bacterial strains. (C) 2011 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molstruc.2011.04.024