1-Bromo-3-(but-3-yn-1-yl)benzene | 1551976-25-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-Bromo-3-(but-3-yn-1-yl)benzene
• 英文别名: 1-bromo-3-but-3-ynylbenzene
• CAS: 1551976-25-0
• 化学式: C₁₀H₉Br
• 分子量: 209.08
• InChiKey: CXCZKYCFWDTEAL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

文献信息

• ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS
  申请人：Addex Pharmaceuticals SA

  公开号：EP1765795A2

  公开（公告）日：2007-03-28
• [EN] NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS<br/>[FR] NOUVEAUC DERIVES ALKYNYL SERVANT DE MODULATEURS DE RECEPTEURS DE GLUTAMATE METABOTROPIQUES
  申请人：ADDEX PHARMACEUTICALS SA

  公开号：WO2005123703A2

  公开（公告）日：2005-12-29

  The present invention relates to novel compounds of formula (I) wherein W, n, X and W’ are defined in the description; invention compounds are modulators of metabotropic glutamate receptors - subtype 5 (“mGluR5”) which are useful for the treatment of central nervous system disorders as well as other disorders modulated by mGluR5 receptors.