4-fluoro-2-pentylphenylamine | 929560-02-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-fluoro-2-pentylphenylamine
• 英文别名: 4-Fluoro-2-pentylaniline
• CAS: 929560-02-1
• 化学式: C₁₁H₁₆FN
• 分子量: 181.253
• InChiKey: QSEKVBUNWWEZND-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• SUBSTITUTED CYCLOALKENE DERIVATIVE
  申请人：Daiichi Sankyo Company, Limited

  公开号：EP1935879B1

  公开（公告）日：2016-05-11
• MACROCYCLIC COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISEASES
  申请人：CS Pharmasciences, Inc.

  公开号：US20160214996A1

  公开（公告）日：2016-07-28

  The compounds and salts of the present invention inhibit kinases, especially the anaplastic lymphoma kinase (ALK) and the HGF receptor tyrosine kinase (RTK) c-Met, and are useful for treating or ameliorating abnormal cell proliferative disorders, such as cancer.
• US7935835B2
  申请人：——

  公开号：US7935835B2

  公开（公告）日：2011-05-03
• USRE43858E1
  申请人：——

  公开号：USRE43858E1

  公开（公告）日：2012-12-11
• [EN] MACROCYCLIC COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISEASES<br/>[FR] COMPOSÉS MACROCYCLIQUES DESTINÉS AU TRAITEMENT DE MALADIES PROLIFÉRATIVES
  申请人：CS THERAPEUTICS INC

  公开号：WO2015050989A2

  公开（公告）日：2015-04-09

  The compounds and salts of the present invention inhibit kinases, especially the anaplastic lymphoma kinase (ALK) and the HGF receptor tyrosine kinase (RTK) c-Met, and are useful for treating or ameliorating abnormal cell proliferative disorders, such as cancer.