Cannabinodivarin | 41408-26-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Cannabinodivarin
• 英文别名: 2-(5-methyl-2-prop-1-en-2-ylphenyl)-5-propylbenzene-1,3-diol
• CAS: 41408-26-8
• 化学式: C₁₉H₂₂O₂
• 分子量: 282.4
• InChiKey: COURSARJQZMTEZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• [EN] METHODS OF SYNTHESIZING HIGH-PURITY CANNABICYCLOL AND ARTIFICIAL RESINS COMPRISING CANNABICYCLOL<br/>[FR] PROCÉDÉS DE SYNTHÈSE DE CANNABICYCLOL DE HAUTE PURETÉ ET RÉSINES ARTIFICIELLES COMPRENANT DE LA CANNABICYCLOL
  申请人：CANOPY GROWTH CORP

  公开号：WO2021127788A1

  公开（公告）日：2021-07-01

  Compositions having enhanced cannabicyclol (CBL) or CBL derivative concentrations are disclosed herein as are methods of synthesizing CBL and CBL derivative in high-purity form. Relative to conventional methods, the methods of the present disclosure may: (i) be better suited to large-scale conditions in that they do not require dangerous and/or toxic solvents and/or reagents; (ii) be more tolerant of complex starting compositions, such as cannabinoid extracts, isolates and/or distillates; (iii) provide CBL and/or CBL derivative at higher yield; (iv) provide easier methods to purify product mixtures comprising CBL and/or CBL derivative; (v) provide product mixtures that comprise unique ratios of CBL or CBL derivative relative to other cannabinoids; (vi) provide product mixtures with reduced THC concentrations and/or (vii) provide artificial resins having of a mixture cannabinoids that cannot be produced by extracting cannabis plant material.

  本文披露了具有增强型大麻环酚（CBL）或CBL衍生物浓度的组合物，以及合成高纯度形式的CBL和CBL衍生物的方法。相对于传统方法，本公开的方法可能：（i）更适合于大规模条件，因为它们不需要危险和/或有毒的溶剂和/或试剂；（ii）更容忍复杂的起始组合物，如大麻提取物、分离物和/或蒸馏液；（iii）提供更高产量的CBL和/或CBL衍生物；（iv）提供更容易纯化含有CBL和/或CBL衍生物的产品混合物的方法；（v）提供相对于其他大麻素具有独特比率的CBL或CBL衍生物的产品混合物；（vi）提供具有降低THC浓度的产品混合物和/或（vii）提供具有无法通过提取大麻植物材料生产的混合大麻素的人工树脂。
• Water soluble compositions comprising purified cannabinoids
  申请人：CANOPY GROWTH CORPORATION

  公开号：US10568865B2

  公开（公告）日：2020-02-25

  This disclosures relates to new compositions and methods for making cannabinoid formulations. In one embodiment, this disclosure provides water soluble compositions comprising a first purified cannabinoid and Vitamin E TPGS. In one embodiment, the disclosure herein comprises a method of making powders comprising heatings material to a first temperature and a second temperature.

  本公开涉及用于制造大麻素制剂的新组合物和方法。在一个实施方案中，本公开提供了包含第一种纯化大麻素和维生素 E TPGS 的水溶性组合物。在一个实施方案中，本公开包括一种制作粉末的方法，包括将材料加热到第一温度和第二温度。
• Bioactive concentrates and uses thereof
  申请人：SC LABORATORIES, INC.

  公开号：US10792318B2

  公开（公告）日：2020-10-06

  The present invention relates to concentrates obtained from extraction from Cannabis, preferably cannabinoid and/or terpene concentrates, and formulation of the concentrates, particularly for use for direct vaporization, infusion into edible matrices, in electronic inhalation devices, and as nutraceuticals.

  本发明涉及从大麻中提取的浓缩物，最好是大麻素和/或萜类浓缩物，以及浓缩物的配方，特别是用于直接汽化、注入可食用基质、电子吸入装置和作为营养保健品。
• Methods and compositions for treating cancer
  申请人：Sutter West Bay Hospitals

  公开号：US11344527B2

  公开（公告）日：2022-05-31

  This disclosure provides compositions and method useful for treating cell proliferative disorders including cancer. The disclosure provides cannabidiol derivatives and compositions thereof either alone or in combination with THC or a derivative thereof.

  本公开提供了用于治疗包括癌症在内的细胞增殖性疾病的组合物和方法。本公开提供了大麻二酚衍生物及其单独或与四氢大麻酚或其衍生物结合使用的组合物。
• METHODS AND COMPOSITIONS FOR TREATING CANCER
  申请人：McAllister Sean D.

  公开号：US20100204312A1

  公开（公告）日：2010-08-12

  This disclosure provides compositions and method useful for treating cell proliferative disorders including cancer. The disclosure provides cannabidiol derivatives and compositions thereof either alone or in combination with THC or a derivative thereof.