3-Aethylmercapto-2-methyl-thiophen | 19991-62-9

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 3-Aethylmercapto-2-methyl-thiophen
• 英文别名: 3-ethylsulfanyl-2-methyl-thiophene；3-Ethylsulfanyl-2-methylthiophene
• CAS: 19991-62-9
• 化学式: C₇H₁₀S₂
• 分子量: 158.288
• InChiKey: JPIBVGFJRKRQMR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  53.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Inhibitors of Protein Tyrosine Phosphatase 1B
  申请人：Lee Jinbo

  公开号：US20090048286A1

  公开（公告）日：2009-02-19

  Protein tyrosine phosphatases (PTPases) such as PTP1B can play a role in regulating a wide variety of cellular responses such as insulin signaling. Substituted bicyclic fused-thiophene compounds can inhibit PTP1B and thereby induce greater insulin sensitivity. Accordingly, PTP1B inhibition can provide an alternate treatment for PTPase-mediated disorders such as diabetes.

  蛋白酪氨酸磷酸酶（PTPases）如PTP1B可以在调节各种细胞响应（如胰岛素信号传导）方面发挥作用。取代的双环融合噻吩化合物可以抑制PTP1B，从而增强胰岛素敏感性。因此，PTP1B的抑制可以提供PTPase介导的疾病（如糖尿病）的另一种治疗方法。
• PERFUME PRECURSOR COMPOSITIONS AND METHOD FOR EXPRESSING PERFUME COMPONENTS
  申请人：Ajinomoto Co., Inc.

  公开号：EP1172432A1

  公开（公告）日：2002-01-16

  Herein is disclosed a flavor precursor composition comprising as an active ingredient a flavor precursor compound (flavor precursor compound A) in which a volatile flavor compound having a mercapto group in the molecule and a non-volatile compound having a mercapto group in the molecule are bound to form a disulfide structure, or a flavor precursor compound (flavor precursor compound B) which is an organic compound represented by Formula (1) shown below in which R1H is a non-volatile compound and R2H is a volatile compound having in the molecule a furan ring structure (including a structure where part or all of the carbon-carbon double bonds thereof are hydrogenated) or a thiophene ring structure (including a structure where part or all of the carbon-carbon double bonds thereof are hydrogenated), said Formula (1) being: which composition can preserve, and release, the flavor effectively and can be used in the fields of fragrances and foods.

  本发明公开了一种香精前体组合物，其活性成分包括香精前体化合物（香精前体化合物A），其中分子中具有巯基的挥发性香精化合物与分子中具有巯基的非挥发性化合物结合形成二硫结构、或一种香料前体化合物（香料前体化合物 B），它是由下式（1）表示的有机化合物，其中 R1H 为非挥发性化合物，R2H 为挥发性化合物，分子中具有呋喃环结构（包括部分或全部碳碳双键氢化的结构）或噻吩环结构（包括部分或全部碳碳双键氢化的结构），所述式（1）为： 该组合物能有效地保存和释放香味，可用于香料和食品领域。
• BICYCLIC COMPOUNDS
  申请人：BASF SE

  公开号：US20190104738A1

  公开（公告）日：2019-04-11

  The present invention relates to compounds of formula I, wherein the variables are defined as given in the description and claims. The invention further relates to uses, processes and composition for compounds I.
• US7011860B1
  申请人：——

  公开号：US7011860B1

  公开（公告）日：2006-03-14