3-甲基-6-[(苯基甲基)胺基]-3H-二苯并[FIJ]异喹啉-2,7-二酮 | 21295-58-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 中文名称: 3-甲基-6-[(苯基甲基)胺基]-3H-二苯并[FIJ]异喹啉-2,7-二酮
• 中文别名: 6-(苄基氨基)-3-甲基-3H-萘并[1,2,3-去]喹啉-2,7-二酮
• 英文名称: 6-benzylamino-3-methyl-3H-naphtho[1,2,3-de]quinoline-2,7-dione
• 英文别名: 6-(benzylamino)-3-methyl-3H-naphtho[1,2,3-de]quinoline-2,7-dione；10-(benzylamino)-14-methyl-14-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1(16),2,4,6,9,11,13(17)-heptaene-8,15-dione
• CAS: 21295-58-9
• 化学式: C₂₄H₁₈N₂O₂
• 分子量: 366.419
• InChiKey: SNRUYODNDNHTNI-UHFFFAOYSA-N

物化性质

• 沸点：
  609.8±55.0 °C(Predicted)
• 密度：
  1.36±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  28
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  49.4
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• CENTRAL NERVOUS SYSTEM TISSUE-LABELING COMPOSITION, METHOD FOR LABELING CENTRAL NERVOUS SYSTEM TISSUE, AND SCREENING METHOD USING CENTRAL NERVOUS SYSTEM TISSUE-LABELING COMPOSITION
  申请人：CANON KABUSHIKI KAISHA

  公开号：US20160361442A1

  公开（公告）日：2016-12-15

  To provide a central nervous system tissue-labeling composition labeling the central nervous tissue system. Also, another object of the present invention is to provide a method for non-invasively labeling the central nervous tissue system. Further, another object of the present invention is to provide a screening method using the above central nervous system tissue-labeling composition. A central nervous system tissue-labeling composition containing, as an active ingredient, at least one of compounds represented by the general formula (1) or (7).

  提供一种中枢神经系统组织标记组合物，用于标记中枢神经系统组织。此外，本发明的另一个目标是提供一种非侵入性标记中枢神经组织系统的方法。进一步，本发明的另一个目标是提供一种使用上述中枢神经系统组织标记组合物的筛选方法。中枢神经系统组织标记组合物包含至少一种由一般式（1）或（7）表示的化合物作为活性成分。
• COMPOSITION FOR LABELING TISSUES OF CENTRAL NERVOUS SYSTEM, METHOD FOR LABELING TISSUES OF CENTRAL NERVOUS SYSTEM, AND SCREENING METHOD USING THE COMPOSITION FOR LABELING TISSUES OF CENTRAL NERVOUS SYSTEM
  申请人：Canon Kabushiki Kaisha

  公开号：EP2399612B1

  公开（公告）日：2018-02-21
• LABELING COMPOSITION FOR INTRAOCULAR TISSUE, LABELING METHOD OF INTRAOCULAR TISSUE, AND SCREENING METHOD
  申请人：Watanabe Kohei

  公开号：US20110236310A1

  公开（公告）日：2011-09-29

  The invention provides a labeling composition for an intraocular tissue of a living individual, which specifically labels the intraocular tissue without need of an invasive operation such as exposure of an ocular tissue or injection of a staining agent into the ocular tissue or a nerve tissue linking to the ocular tissue, a method of noninvasively labeling an intraocular tissue of a living individual, and a screening method using the labeling composition for the intraocular tissues. The composition contains a compound capable of labeling at least a photoreceptor cell layer of a retina, wherein the compound is a staining compound having a particular structure as a partial structure thereof.
• US9764046B2
  申请人：——

  公开号：US9764046B2

  公开（公告）日：2017-09-19