3-[(3,5-bis[N-[3,5-bis(methoxycarbonyl)phenyl]carbamoyl]phenyl)carbonylamino]-5-(methoxycarbonyl)benzoic acid methyl ester | 69318-25-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-[(3,5-bis[N-[3,5-bis(methoxycarbonyl)phenyl]carbamoyl]phenyl)carbonylamino]-5-(methoxycarbonyl)benzoic acid methyl ester
• 英文别名: methyl 3-[(3,5-bis{N-[3,5-bis(methoxycarbonyl)phenyl]carbamoyl}phenyl)-carbonylamino]-5-(methoxycarbonyl)benzoate；1-N,3-N,5-N-tris[3,5-bis(methoxycarbonyl)phenyl]benzene-1,3,5-tricarboximidic acid
• CAS: 69318-25-8
• 化学式: C₃₉H₃₃N₃O₁₅
• 分子量: 783.702
• InChiKey: WDDFLSSMSVLOMQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  57
• 可旋转键数：
  18
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  245
• 氢给体数：
  3
• 氢受体数：
  15

文献信息

• Benzene tricarboxylic acid derivatives as insulin receptor activators
  申请人：——

  公开号：US20020103183A1

  公开（公告）日：2002-08-01

  Compounds of Formula I, and pharmaceutical compositions containing these compounds, activate the insulin receptor kinase, which leads to an increased sensitivity to insulin and an increase in glucose uptake, and are therefore useful for the treatment of animals, especially humans, with hyperglycemia, especially for the treatment of type 2 diabetes. Processes for preparation of the compounds, and their use in assays, are also disclosed.

  公式I的化合物及含有这些化合物的制药组合物，可以激活胰岛素受体激酶，从而提高对胰岛素的敏感性和葡萄糖摄取量，因此可用于治疗动物，尤其是人类的高血糖，特别是用于治疗2型糖尿病。还公开了制备这些化合物的过程以及它们在测定中的应用。
• BENZENE TRICARBOXYLIC ACID AMIDES AS INSULIN RECEPTOR ACTIVATORS
  申请人：TELIK, INC.

  公开号：EP1315695B1

  公开（公告）日：2005-07-13
• COMPOSITION FOR FORMING RESIST UNDERLAYER
  申请人：AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L.

  公开号：US20150118624A1

  公开（公告）日：2015-04-30

  The present invention provides a dendrimer compound capable of improving critical dimension uniformity and DOF (depth of focus) margin, and also provides a composition capable of forming an underlayer film. The dendrimer compound comprises a branched chain having a central aromatic skeleton and amide or ester bond, and is contained in the composition for forming an underlayer film.
• US6600069B2
  申请人：——

  公开号：US6600069B2

  公开（公告）日：2003-07-29
• US9328198B2
  申请人：——

  公开号：US9328198B2

  公开（公告）日：2016-05-03