N4,N4'-diethyl-3,3'-dimethyl-[1,1'-biphenyl]-4,4'-diamine | 55230-01-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N4,N4'-diethyl-3,3'-dimethyl-[1,1'-biphenyl]-4,4'-diamine
• 英文别名: N⁴,N^4'-diethyl-3,3'-dimethyl-[1,1'-biphenyl]-4,4'-diamine
• CAS: 55230-01-8
• 化学式: C₁₈H₂₄N₂
• 分子量: 268.402
• InChiKey: CMEWPWHPUQHVBF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.83
• 重原子数：
  20.0
• 可旋转键数：
  5.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  24.06
• 氢给体数：
  2.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  N-乙基-邻甲苯胺 在 iron(III) chloride hexahydrate 作用下， 以 甲苯 为溶剂， 反应 2.0h， 以28%的产率得到N4,N4'-diethyl-3,3'-dimethyl-[1,1'-biphenyl]-4,4'-diamine
  参考文献：
  名称：

  Extension studies on iron(III)-promoted free radical oxidation of anilines: self-coupling and self-bridged assembling reactions

  摘要：

  The iron(III)-promoted free radical oxidation of anilines has been further developed. Anilines including those bearing strong electron-withdrawing groups on benzene ring were readily converted into corresponding self-coupling benzidines. With addition of base, the methyl on nitrogen was activated and the free radical oxidations tended to furnish the corresponding self-bridged assembling diaminodiarylmethanes. (C) 2015 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2015.06.018