4-(phenyltellanyl)benzoic acid | 1386388-88-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(phenyltellanyl)benzoic acid
• CAS: 1386388-88-0
• 化学式: C₁₃H₁₀O₂Te
• 分子量: 325.821
• InChiKey: VHVQXZIJMHKNSR-UHFFFAOYSA-N

物化性质

• 熔点：
  160-162 °C

计算性质

• 辛醇/水分配系数(LogP)：
  1.04
• 重原子数：
  16.0
• 可旋转键数：
  3.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  37.3
• 氢给体数：
  1.0
• 氢受体数：
  1.0

反应信息

• 作为产物：
  描述：

  联苯二碲 、 4-羧基苯硼酸 在 sodium tetrahydroborate 、 copper(l) iodide 、 1,10-菲罗啉 作用下， 以 乙醇 为溶剂， 反应 5.0h， 以68%的产率得到4-(phenyltellanyl)benzoic acid
  参考文献：
  名称：

  A convenient and efficient copper-catalyzed synthesis of unsymmetrical and symmetrical diaryl chalcogenides from arylboronic acids in ethanol at room temperature

  摘要：

  A simple and convenient approach for the synthesis of unsymmetrical diaryl chalcogenides (Te, Se, and S) has been developed by copper-catalyzed cross-coupling reaction of organoboronic acid with diaryl dichalcogenide in ethanol using NaBH4 in air or oxygen. The present methodology is highly practical for the synthesis of unsymmetrical diaryl tellurides with various functionalities such as -NO2, -F, -Br, and -COOH that have been obtained in good to excellent yields. Methodology is also effective for the synthesis of unsymmetrical diaryl selenides and sulfides. Moreover, symmetrical diaryl selenides have also been obtained from arylboronic acids using elemental selenium powder under optimized reaction conditions. The use of NaBH4 is the key for the development of milder reaction conditions, which enable the construction of unsymmetrical diaryl chalcogenides from boronic acid substrates in ethanol at room temperature. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2014.01.030

文献信息

• Microwave-assisted reaction of aryl diazonium fluoroborate and diaryl dichalcogenides in dimethyl carbonate: a general procedure for the synthesis of unsymmetrical diaryl chalcogenides
  作者：Debasish Kundu、Sabir Ahammed、Brindaban C. Ranu

  DOI：10.1039/c2gc35328h

  日期：——

  A convenient, general and efficient procedure for the synthesis of unsymmetrical diaryl chalcogenides has been developed by the reaction of aryl diazonium fluoroborates and diaryl dichalcogenides in the presence of zinc dust in dimethyl carbonate under microwave irradiation. The reactions of a wide range of substituted aryl diazonium fluoroborates and diaryl dichalcogenides have been addressed. The

  通过在碳酸二甲酯中的锌粉存在下，在微波辐射下，使芳基重氮氟硼酸酯与二芳基二卤化氢在碳酸二甲酯存在下反应，已经开发出一种方便，通用且有效的合成不对称二芳基硫属元素化物的方法。已经解决了广泛范围的取代的氟硼酸重氮芳基酯和二芳基二卤化氢的反应。裂解二芳基二卤化氢需要锌粉。快速干燥后获得高纯度产品柱层析 后的原油残留量 蒸发 碳酸二甲酯。