6-Bromo-3-fluoro-2-vinylpyridine | 1684434-01-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 6-Bromo-3-fluoro-2-vinylpyridine
• 英文别名: 6-bromo-2-ethenyl-3-fluoropyridine
• CAS: 1684434-01-2
• 化学式: C₇H₅BrFN
• 分子量: 202.02
• InChiKey: TUZDHLXHVRUPPD-UHFFFAOYSA-N

物化性质

• 沸点：
  212.0±40.0 °C(Predicted)
• 密度：
  1.566±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] 6-SUBSTITUTED 3-FLUORO-2-PYRIDINALDOXIME, 3-FLUORO-2-PYRIDINE HYDROXAMIC ACID, AND 3-FLUORO-2-PYRIDINAMIDOXIME SCAFFOLDS<br/>[FR] 3-FLUORO-2-PYRIDINALDOXIME À SUBSTITUTION EN POSITION 6, ACIDE HYDROXAMIQUE DE 3-FLUORO-2-PYRIDINE ET ÉCHAFAUDAGES DE 3-FLUORO-2-PYRIDINAMIDOXIME
  申请人：CENTRE NAT RECH SCIENT

  公开号：WO2019076986A1

  公开（公告）日：2019-04-25

  The present invention relates to a compound of formula (II), as well as to a process for preparing the compounds of formula (II) by a chemoselective Sonogashira reaction. It also relates to a pharmaceutical composition comprising at least one compound of formula (II) and at least one pharmaceutically acceptable support. Finally, it relates to the use of such a compound as a medicine, preferably in the treatment of a nervous and/or respiratory failure due to intoxication with at least one organophosphorous nerve agent; in the treatment of neurological diseases such as Alzheimer's disease; and/or in the treatment of cancer; and/or for use as antiviral drug.