2-(diisopropylphosphino)benzenesulfonic acid | 732951-35-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(diisopropylphosphino)benzenesulfonic acid
• 英文别名: 2-Di(propan-2-yl)phosphaniumylbenzenesulfonate
• CAS: 732951-35-8
• 化学式: C₁₂H₁₉O₃PS
• 分子量: 274.321
• InChiKey: QSABYDIVRXXXCV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  65.6
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• CARBOXYLATE METAL COMPLEX AND CATALYST FOR OLEFIN POLYMERIZATION
  申请人：Ito Shingo

  公开号：US20130158223A1

  公开（公告）日：2013-06-20

  The present invention provides a metal complex of group 10 elements of the periodic table having a carboxylate structure represented by formula (C2); a catalyst for polymerization of olefin mainly comprising the metal complex; and a method for producing polymers by homopolymerizing olefin represented by formula (1), polymerizing two or more kinds of the above olefin, or copolymerizing olefin represented by formula (1) with polar group-containing olefin represented by formula (2) (the meaning of the symbols are as set forth in the description) using the catalyst. A metal complex of group 10 elements of the periodic table, in which all of the coordinating atoms to the metal are a hetero atom is stable and useful as a catalyst component for olefin polymerization, and can be used for a long time in homopolymerization of olefin or copolymerization of two or more kinds of olefin.

  本发明提供了一种具有由式（C2）表示的羧酸盐结构的周期表第10族元素的金属配合物；主要包括所述金属配合物的烯烃聚合催化剂；以及通过使用所述催化剂，通过将由式（1）表示的烯烃进行均聚合，聚合两种或更多种上述烯烃，或将由式（1）表示的烯烃与由式（2）表示的含极性基团的烯烃进行共聚合来生产聚合物的方法。周期表第10族元素的金属配合物，其中与金属配位的所有原子均为杂原子，稳定且可用作烯烃聚合的催化剂组分，并可在烯烃的均聚合或两种或更多种烯烃的共聚合中长时间使用。
• METHOD FOR PRODUCING COPOLYMER OF ALLYL MONOMER HAVING POLAR GROUP
  申请人：The University of Tokyo

  公开号：EP3786196A1

  公开（公告）日：2021-03-03

  The present invention pertains to a method for producing a copolymer of ethylene and an allyl monomer having a polar group represented by general formula (1), or a copolymer of ethylene, an allyl monomer having a polar group represented by general formula (1), and other monomers, wherein the copolymer is produced in the presence of a boron compound having a boron-hydrogen bond or a boron-carbon bond (for example, a compound represented by general formula (2)) by using a metal complex represented by general formula (C1) as a polymerization catalyst (the symbols in the formulas are as described in the description). According to the present invention, a copolymer of ethylene and an allyl monomer can be efficiently produced with high catalytic activity, wherein the copolymer has a polar group and can be used in various applications.

  本发明涉及一种生产乙烯和具有通式(1)表示的极性基团的烯丙基单体的共聚物，或乙烯、具有通式(1)表示的极性基团的烯丙基单体和其他单体的共聚物的方法、其中，该共聚物是在具有硼-氢键或硼-碳键的硼化合物（例如通式（2）所代表的化合物）存在下，通过使用通式（C1）所代表的金属络合物作为聚合催化剂生产的（式中符号如说明中所描述）。根据本发明，可以高效地生产出具有高催化活性的乙烯和烯丙基单体的共聚物，其中共聚物具有极性基团，可用于各种用途。
• Selective reduction of cysteine-engineered antibodies
  申请人：Byondis B.V.

  公开号：US10814009B2

  公开（公告）日：2020-10-27

  The present invention relates to a process for the selective reduction of cysteine-engineered antibodies comprising reacting an antibody comprising one or more engineered cysteines at positions selected from HC40, HC41,HC42, HC89, HC152, HC153, HC155, HC171, LC40, LC41, LC165, and LC168 with a compound according to formula (I), (II), (III), (IV), (V), (VI) or (VII): (I) (II) (III) (IV) (V) (VI) (VII), and to a process for the preparation of antibody conjugates, including antibody-drug conjugates (ADCs).

  本发明涉及一种选择性还原半胱氨酸工程化抗体的工艺，包括将在选自 HC40、HC41、HC42、HC89、HC152、HC153、HC155、HC171、LC40、LC41、LC165 和 LC168 的位置上包含一个或多个工程化半胱氨酸的抗体与根据式(I)、(II)、(III)、(IV)、(V)、(VI)或(VII)的化合物反应：(I)(II)(III)(IV)(V)(VI)(VII)的化合物，以及制备抗体共轭物，包括抗体-药物共轭物（ADC）的工艺。
• Method for producing copolymer of polar group-containing allyl monomer
  申请人：THE UNIVERSITY OF TOKYO

  公开号：US11248074B2

  公开（公告）日：2022-02-15

  The present invention relates to a method for producing a copolymer of ethylene and an allyl monomer that is represented by formula (1) and has a polar group, or a copolymer of ethylene, the allyl monomer that is represented by formula (1) and has a polar group, and another monomer. This production method is characterized by using a metal complex, which is represented by general formula (C1), as a polymerization catalyst and by having a silane compound, which is represented by general formula (2) and has a silicon-hydrogen bond, coexist with the metal complex. (In the formulae, the symbols are as defined in the description.) According to the present invention, a copolymer of an allyl monomer that has a polar group is able to be produced with high catalytic activity, said copolymer being capable of having various applications.

  本发明涉及一种生产乙烯和烯丙基单体的共聚物的方法，乙烯和烯丙基单体由式(1)表示并带有极性基团，或乙烯、由式(1)表示并带有极性基团的烯丙基单体和另一种单体的共聚物。这种生产方法的特点是使用通式（C1）表示的金属络合物作为聚合催化剂，并使通式（2）表示的具有硅氢键的硅烷化合物与金属络合物共存。(根据本发明，可以生产出一种具有极性基团的烯丙基单体的共聚物，该共聚物具有很高的催化活性，可以有多种用途。
• PRODUCTION METHOD OF COPOLYMER OF ALLYL MONOMER CONTAINING POLAR GROUP
  申请人：The University of Tokyo

  公开号：EP2470575A2

  公开（公告）日：2012-07-04