N-[4-(Aminoiminomethyl)phenyl]benzamide | 53032-87-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-[4-(Aminoiminomethyl)phenyl]benzamide
• 英文别名: N-(4-carbamimidoylphenyl)benzamide
• CAS: 53032-87-4
• 化学式: C₁₄H₁₃N₃O
• 分子量: 239.27
• InChiKey: OHNFFGJZFZVGKZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  79
• 氢给体数：
  3
• 氢受体数：
  2

文献信息

• COOLING COMPOUNDS
  申请人：Givaudan SA

  公开号：EP1860960A1

  公开（公告）日：2007-12-05
• Cooling Compounds
  申请人：Cole Lucienne

  公开号：US20080319055A1

  公开（公告）日：2008-12-25

  A method of providing a cooling sensation to the skin or the mucous membranes of the body by applying thereto a compound of Formula I in which X is H or (CH 2 ) n —R, n is 0 or 1, Y and Z are selected independently from the group consisting of H, OH, phenyl, C1-C4 straight or branched alkyl, or, a C 1 -C 4 straight or branched alkoxy, or X and Y form together a bivalent radical selected from the group consisting of —O—CH 2 —O—, —N═CH—O— and —N═CH—S— which forms together with the carbon atoms to which they are attached a 5-membered ring; and R is a group with non-bonding electrons, R 1 is H or C 1 -C 5 branched alkyl, R2 and R3 are C 1 -C4 branched alkyls, or R 2 and R 3 taken together form a monocyclic, bicyclic or tricyclic radical of up to 10 carbons provided that R 1 , R 2 and R 3 together comprise at least 6 carbons. The compounds may be incorporated into products such as dentifrices, foodstuffs, confectionery, beverages, and cosmetic and medicinal preparations.
• [EN] COOLING COMPOUNDS<br/>[FR] COMPOSES FRIGORIGENES
  申请人：GIVAUDAN SA

  公开号：WO2006099762A1

  公开（公告）日：2006-09-28

  [EN] A method of providing a cooling sensation to the skin or the mucous membranes of the body by applying thereto a compound of Formula (I) in which X is H or (CH₂)_n-R, n is 0 or 1, Y and Z are selected independently from the group consisting of H, OH, phenyl, C1-C4 straight or branched alkyl, or, a C₁-C₄ straight or branched alkoxy, or X and Y form together a bivalent radical selected from the group consisting of -O-CH₂-O-, -N=CH-O- and -N=CH-S- which forms together with the carbon atoms to which they are attached a 5-membered ring; and R is a group with non-bonding electrons, R¹ is H or C₁-C₅ branched alkyl, R2 and R3 are C₁-C4 branched alkyls, or R² and R³ taken together form a monocyclic, bicyclic or tricyclic radical of up to 10 carbons provided that R¹, R² and R³ together comprise at least 6 carbons. The compounds may be incorporated into products such as dentifrices, foodstuffs, confectionery, beverages, and cosmetic and medicinal preparations.
  [FR] L'invention concerne une méthode permettant d'apporter une sensation de refroidissement à la peau ou aux muqueuses du corps, en leur appliquant un composé de Formule I, où X est H ou (CH₂)_n-R, n est 0 ou 1, Y et Z sont choisis indépendamment parmi le groupe consistant en H, OH, phényle, alkyle en C₁-C₄ linéaire ou ramifié, alcoxy en C₁-C₄ linéaire ou ramifié, ou X et Y forment ensemble un radical bivalent choisi parmi le groupe consistant en -O-CH₂-O-, -N=CH-O- et -N=CH-S-, qui forme avec les atomes de carbone auxquels ils sont rattachés un cycle à 5 chaînons ; et R est un groupement avec des électrons non-liants, R¹ est H ou un alkyle ramifié en C₁-C₅, R² et R³ sont des alkyles ramifiés en C₁-C₄, ou R² et R³ forment ensemble un radical monocyclique, bicyclique ou tricyclique contenant jusqu'à 10 carbones à condition que R¹, R² et R³ contiennent au total au moins 6 carbones. Ces composés peuvent être incorporés dans des produits tels que des dentifrices, des denrées alimentaires, des confiseries, des boissons, ainsi que des cosmétiques et des préparations médicinales.