1,3-thiazol-5-ylmethyl N-[(2R,5R)-5-(butan-2-ylsulfonylamino)-1,6-diphenylhexan-2-yl]carbamate | 1383580-89-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,3-thiazol-5-ylmethyl N-[(2R,5R)-5-(butan-2-ylsulfonylamino)-1,6-diphenylhexan-2-yl]carbamate
• CAS: 1383580-89-9
• 化学式: C₂₇H₃₅N₃O₄S₂
• 分子量: 529.725
• InChiKey: ZUJHHCOUKVXLJW-LYWQJQBASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  36
• 可旋转键数：
  15
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.41
• 拓扑面积：
  134
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• INHIBITORS OF CYTOCHROME P450
  申请人：Desai Manoj C.

  公开号：US20130280212A1

  公开（公告）日：2013-10-24

  The present application provides for a compound of formula (I), or a pharmaceutically acceptable salt, solvate, and/or ester thereof, compositions containing such compounds, therapeutic methods that include the administration of such compounds, and therapeutic methods that include the administration of such compounds with at least one additional therapeutic agent.