17-methyloxacycloheptadecan-2-one | 111908-52-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 大环内酯类和类似物
• 英文名称: 17-methyloxacycloheptadecan-2-one
• 英文别名: 17-Methyl-1-oxacycloheptadecan-2-one；17-methyl-oxacycloheptadecan-2-one
• CAS: 111908-52-2
• 化学式: C₁₇H₃₂O₂
• 分子量: 268.44
• InChiKey: PNXDPYXFAFMSNJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  19
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• PROCESS FOR PREPARING UNSATURATED LACTONES
  申请人：Meijer John

  公开号：US20090306411A1

  公开（公告）日：2009-12-10

  The invention relates to a process for preparing saturated or unsaturated lactones. This process involves reacting a bicyclic compound or a monocyclic compound with hydrogen peroxide in the presence of a first acid having a pK a of 3 or less and a first organic solvent, thereby forming a hydroperoxide. The obtained mixture comprising the hydroperoxide is subsequently metered to a mixture of a second organic solvent and a dissociation-enhancing catalyst, optionally comprising a second organic acid. The invention also pertains to a process of preparing the hydroperoxide.

  本发明涉及一种制备饱和或不饱和内酯的方法。该方法涉及在第一有机溶剂中，在第一酸(pKa小于或等于3)的存在下，将双环化合物或单环化合物与过氧化氢反应，从而形成一个过氧化物。随后，将包含过氧化物的混合物滴加到第二有机溶剂和促进解离的催化剂混合物中，可选地包括第二有机酸。本发明还涉及制备过氧化物的方法。
• [EN] PROCESS FOR PREPARING UNSATURATED LACTONES<br/>[FR] PROCEDE DE PREPARATION DE LACTONES INSATURES
  申请人：SYMRISE GMBH & CO KG

  公开号：WO2005113533A9

  公开（公告）日：2009-09-24
• MACROCYCLIC MUSK LACTONES AND USES THEREOF
  申请人：Blue California

  公开号：US20220298451A1

  公开（公告）日：2022-09-22

  Provided herein are uses of lactones, such as macrocyclic lactones, for use in consumer products.
• US8383834B2
  申请人：——

  公开号：US8383834B2

  公开（公告）日：2013-02-26
• [EN] BIOSYNTHETIC PRODUCTION OF MACROCYCLIC MUSK LACTONES FROM FATTY ACIDS<br/>[FR] PRODUCTION BIOSYNTHÉTIQUE DE LACTONES DE MUSC MACROCYCLIQUES À PARTIR D'ACIDES GRAS
  申请人：[en]CONAGEN INC.

  公开号：WO2022192384A1

  公开（公告）日：2022-09-15

  Provided herein are biosynthetic methods for producing lactones, such as macrocyclic lactones, from fatty acids. The lactones produced using and/or during the biosynthetic methods are also provided.